Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | WDR5 | P61964 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30035302 | 1.00 | ALDH1A1 (0.59) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL2620528 | 0.88 | ESR1 (0.57) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL15457920 | 0.83 | ALDH1A1 (0.59) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL13894365 | 0.82 | MEN1 (0.62) | ALOX15HSD17B10MEN1KMT2AGAA | |
| SCHEMBL1265209 | 0.81 | ESR1 (0.46) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL4211344 | 0.79 | ALDH1A1 (0.53) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL2620521 | 0.79 | MEN1 (0.46) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL14354625 | 0.77 | POLB (0.54) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL21140989 | 0.77 | ALDH1A1 (0.52) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL12115605 | 0.77 | MAPT (0.58) | ALDH1A1HPGDALOX15HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3638647-B1 | PROCESS FOR MONO N-ALKYLATION OF AMINOPHENOL | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2024-01-17 | — | — | EP | disclosed |
| EP-3638647-B1 | PROCESS FOR MONO N-ALKYLATION OF AMINOPHENOL | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2024-01-17 | — | — | EP | disclosed |
| EP-3353146-B1 | SYNTHESIS OF SUBSTITUTED AMIDOBENZOATE COMPOUNDS, THE COMPOUNDS OBTAINED AND THE USE THEREOF AS PHTHALATE FREE INTERNAL ELECTRON DONOR FOR POLYMERIZATION OF OLEFINS | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2023-10-25 | — | — | EP | disclosed |
| EP-3353146-B1 | SYNTHESIS OF SUBSTITUTED AMIDOBENZOATE COMPOUNDS, THE COMPOUNDS OBTAINED AND THE USE THEREOF AS PHTHALATE FREE INTERNAL ELECTRON DONOR FOR POLYMERIZATION OF OLEFINS | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2023-10-25 | — | — | EP | disclosed |
| CN-110740987-B | Method for mono-N-alkylation of aminophenols | SABIC环球技术有限责任公司 | 2023-04-21 | — | — | CN | disclosed |
| CN-108349873-B | Synthesis of substituted amidobenzoate compounds and their use as phthalate-free internal electron donors | SABIC环球技术有限责任公司 | 2022-12-23 | — | — | CN | disclosed |
| US-11066354-B2 | Process for mono N-alkylation of aminophenol | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2021-07-20 | — | — | US | disclosed |
| US-11066354-B2 | Process for mono N-alkylation of aminophenol | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2021-07-20 | — | — | US | disclosed |
| US-20200140373-A1 | PROCESS FOR MONO N-ALKYLATION OF AMINOPHENOL | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2020-05-07 | — | — | US | disclosed |
| US-20200140373-A1 | PROCESS FOR MONO N-ALKYLATION OF AMINOPHENOL | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2020-05-07 | — | — | US | disclosed |
| CN-108349873-A | Synthesis of substituted amidobenzoate compounds, the compounds obtained and use of said compounds as phthalate-free internal electron donors for polymerizing olefins | SABIC环球技术有限责任公司 | 2018-07-31 | — | — | CN | disclosed |
| WO-2017050870-A9 | SYNTHESIS OF SUBSTITUTED AMIDOBENZOATE COMPOUNDS, THE COMPOUNDS OBTAINED AND THE USE THEREOF AS PHTHALATE FREE INTERNAL ELECTRON DONOR FOR POLYMERIZATION OF OLEFINS | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2018-01-25 | — | — | WO | disclosed |
| WO-2017050870-A9 | SYNTHESIS OF SUBSTITUTED AMIDOBENZOATE COMPOUNDS, THE COMPOUNDS OBTAINED AND THE USE THEREOF AS PHTHALATE FREE INTERNAL ELECTRON DONOR FOR POLYMERIZATION OF OLEFINS | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2018-01-25 | — | — | WO | disclosed |
| US-9845318-B2 | Class of near infrared optical probes for biological applications | THE UNIVERSITY OF AKRON (US) | 2017-12-19 | — | — | US | disclosed |
| WO-2017050870-A1 | SYNTHESIS OF SUBSTITUTED AMIDOBENZOATE COMPOUNDS, THE COMPOUNDS OBTAINED AND THE USE THEREOF AS PHTHALATE FREE INTERNAL ELECTRON DONOR FOR POLYMERIZATION OF OLEFINS | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2017-03-30 | — | — | WO | disclosed |
| WO-2017050870-A1 | SYNTHESIS OF SUBSTITUTED AMIDOBENZOATE COMPOUNDS, THE COMPOUNDS OBTAINED AND THE USE THEREOF AS PHTHALATE FREE INTERNAL ELECTRON DONOR FOR POLYMERIZATION OF OLEFINS | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2017-03-30 | — | — | WO | disclosed |
| WO-2009055357-A1 | DIAZEPANE COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-30 | — | — | WO | disclosed |
| EP-1633715-B1 | 2-(6-AMINO-PYRIDIN-3-YL)-2-HYDROXYETHYLAMINE DERIVATIVES AS BETA 2-ADRENOCEPTORS AGONISTS | PFIZER LTD (GB) | 2007-09-05 | — | — | EP | disclosed |
| EP-1773816-A2 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | Vertex Pharmaceuticals Incorporated (US) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006002421-A2 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2006-01-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11066354-B2 | Process for mono N-alkylation of aminophenol | CYP4A11, CYP4B1, TYR | ALDH1A1 1130/4885HPGD 2251/4885ALOX15 608/4885 |
| US-20200140373-A1 | PROCESS FOR MONO N-ALKYLATION OF AMINOPHENOL | CYP4A11, CYP4B1, TYR | ALDH1A1 1130/4885HPGD 2251/4885ALOX15 608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.