Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.41 |
| ▸ | WDR5 | P61964 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29441554 | 0.89 | ESR1 (0.52) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL4219878 | 0.89 | ESR1 (0.52) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL31419840 | 0.89 | ESR1 (0.52) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL30035302 | 0.79 | ALDH1A1 (0.59) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL5486791 | 0.79 | ALDH1A1 (0.59) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL4543829 | 0.76 | IDO1 (0.50) | MAPTIDO1HDAC2 | |
| SCHEMBL4968569 | 0.76 | ALDH1A1 (0.43) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL28091168 | 0.75 | GAA (0.49) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL20393776 | 0.74 | CYP2C19 (0.37) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL20393607 | 0.74 | GAA (0.41) | ALDH1A1HPGDALOX15HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498467-B2 | Antioxidant and bisaminophenol derivative | IDEMITSU KOSAN CO., LTD. (JP) | 2009-03-03 | — | — | US | disclosed |
| US-20080161608-A1 | ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE | IDEMITSU KOSAN CO., LTD. (JP) | 2008-07-03 | — | — | US | disclosed |
| US-20060208227-A1 | Antioxidant and bisaminophenol derivative | IDEMITSU LOSAN CO., LTD (JP) | 2006-09-21 | — | — | US | disclosed |
| EP-1612254-A1 | ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE | IDEMITSU KOSAN COMPANY LIMITED (JP) | 2006-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161608-A1 | ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE | CBR1, CBR3, HMOX1 | ALDH1A1 204/4885HPGD 208/4885ALOX15 1352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.