Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5329174 | 0.82 | — | — | |
| SCHEMBL5329170 | 0.82 | — | — | |
| SCHEMBL4820336 | 0.79 | ALDH1A1 (0.33) | MAPK1TSHRGAAL3MBTL1ALDH1A1 | |
| SCHEMBL5334653 | 0.78 | MAPK1 (0.33) | MAPK1TSHRGAAL3MBTL1ALDH1A1 | |
| SCHEMBL4817198 | 0.76 | USP2 (0.37) | MAPK1GAAL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL5328026 | 0.76 | L3MBTL1 (0.32) | MAPK1TSHRL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5328032 | 0.76 | L3MBTL1 (0.32) | MAPK1TSHRL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5593127 | 0.76 | TSHR (0.35) | MAPK1TSHRGAAL3MBTL1ALDH1A1 | |
| SCHEMBL4821067 | 0.76 | ALDH1A1 (0.32) | MAPK1TSHRGAAL3MBTL1ALDH1A1 | |
| SCHEMBL4818487 | 0.76 | ENPP1 (0.34) | MAPK1TSHRGAAL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007147829-A1 | AZOLOPYRIMIDINE COMPOUNDS AND THEIR USE FOR CONTROLLING HARMFUL FUNGI | BASF SE (DE) | 2007-12-27 | — | — | WO | disclosed |