SCHEMBL5486977

SCHEMBL5486977

C=CCc1cc(CC=C)c(CC=C)c(N)c1CC=C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 3/20 0.38
GABRB2 P47870 3/20 0.38
POLB P06746 4/20 0.33
IMPDH2 P12268 1/20 0.33
NPSR1 Q6W5P4 1/20 0.32
CYP3A4 P08684 2/20 0.31
MAPT P10636 2/20 0.31
CYP1A2 P05177 1/20 0.31
XDH P47989 1/20 0.30
MEN1 O00255 1/20 0.30
ALOX5 P09917 1/20 0.30
GAA P10253 1/20 0.30
GABRB1 P18505 1/20 0.30
RXRA P19793 1/20 0.30
CNR1 P21554 1/20 0.30
GABRA5 P31644 1/20 0.30
GABRA3 P34903 1/20 0.30
CNR2 P34972 1/20 0.30
GABRA2 P47869 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28789107 0.86 GABRA1 (0.38) GABRA1GABRB2POLBIMPDH2NPSR1
SCHEMBL6278626 0.82 GABRA1 (0.41) GABRA1GABRB2POLBNPSR1CYP3A4
SCHEMBL9244533 0.80 GABRA1 (0.34) GABRA1GABRB2POLBIMPDH2
SCHEMBL9861964 0.80 GABRA1 (0.43) GABRA1GABRB2POLBNPSR1MAPT
SCHEMBL28716719 0.79 NPSR1 (0.38) IMPDH2NPSR1
SCHEMBL5135211 0.77 GABRA1 (0.35) GABRA1GABRB2POLBIMPDH2NPSR1
SCHEMBL10614500 0.77 GABRA1 (0.35) GABRA1GABRB2POLB
SCHEMBL5178926 0.76 GABRA1 (0.47) GABRA1GABRB2POLBNPSR1MAPT
SCHEMBL44699 0.76 GABRA1 (0.48) GABRA1GABRB2POLBNPSR1CYP3A4
SCHEMBL10708328 0.76 GABRA1 (0.34) GABRA1GABRB2POLBIMPDH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070098966-A1 Patterned transfer of metallic elements using photo-degradable polymer templates HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2007-05-03 US disclosed