Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.37 |
| ▸ | TNKS | O95271 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 2/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27689112 | 0.82 | GABRA1 (0.47) | GABRA1GABRB2KDM4EGAAGLA | |
| SCHEMBL15389161 | 0.82 | GABRA1 (0.47) | GABRA1GABRB2KDM4EGAAGLA | |
| SCHEMBL5486977 | 0.80 | GABRA1 (0.38) | GABRA1GABRB2GAAPOLBXDH | |
| SCHEMBL27592056 | 0.79 | GABRA1 (0.47) | GABRA1GABRB2KDM4EGAAGLA | |
| SCHEMBL1245217 | 0.76 | GABRA1 (0.48) | GABRA1GABRB2KDM4EGAAGLA | |
| SCHEMBL25195394 | 0.76 | GABRA1 (0.42) | GABRA1GABRB2GAAPOLBAKR1B1 | |
| SCHEMBL5178926 | 0.76 | GABRA1 (0.47) | GABRA1GABRB2KDM4EGAAGLA | |
| SCHEMBL28295987 | 0.76 | GABRA1 (0.48) | GABRA1GABRB2KDM4EGAAPOLB | |
| SCHEMBL3045553 | 0.75 | GABRA1 (0.47) | GABRA1GABRB2KDM4EGAAGLA | |
| SCHEMBL11874173 | 0.73 | XDH (0.45) | GABRA1GABRB2KDM4EGAAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0246112-B1 | PREPARATION OF DIAMINO- AND DIALKYLAMINOBENZENEDIOLS | THE DOW CHEMICAL COMPANY (US) | 1991-06-12 | — | — | EP | claimed |