Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | BCL9 | O00512 | 1/20 | 0.49 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 2/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.42 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.42 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2721445 | 0.88 | GAA (0.54) | GAABCL9CTNNB1HTR2ASMN1; SMN2 | |
| SCHEMBL1461897 | 0.84 | ELANE (0.60) | GAABCL9CTNNB1HTR2ASMN1; SMN2 | |
| SCHEMBL28011502 | 0.84 | GAA (0.53) | GAABCL9CTNNB1HTR2ASMN1; SMN2 | |
| SCHEMBL7673294 | 0.83 | GAA (0.49) | GAABCL9CTNNB1HTR2ASMN1; SMN2 | |
| SCHEMBL6348206 | 0.81 | BCL9 (0.51) | GAABCL9CTNNB1HTR2ASMN1; SMN2 | |
| SCHEMBL1118843 | 0.81 | ALDH1A1 (0.50) | GAABCL9CTNNB1HTR2ASMN1; SMN2 | |
| SCHEMBL763093 | 0.81 | BCL9 (0.54) | GAABCL9CTNNB1HTR2ASMN1; SMN2 | |
| SCHEMBL11423460 | 0.79 | BCL9 (0.49) | GAABCL9CTNNB1HTR2ASMN1; SMN2 | |
| SCHEMBL7412943 | 0.79 | GAA (0.51) | GAABCL9CTNNB1HTR2ASMN1; SMN2 | |
| SCHEMBL6359040 | 0.79 | BCL9 (0.56) | GAABCL9CTNNB1HTR2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242059-B1 | NOVEL PRODRUGS FOR ANTIMICROBIAL AMIDINES | UNIV NORTH CAROLINA (US) | 2007-03-21 | — | — | EP | disclosed |