Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.50 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.42 |
| ▸ | GRM3 | Q14832 | 4/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3421589 | 0.83 | CYP4F2 (0.47) | CYP4F2CYP4A11FFAR1KDM1AMAOA | |
| SCHEMBL30967881 | 0.79 | FFAR1 (0.51) | CYP4F2CYP4A11FFAR1KDM1AMAOA | |
| SCHEMBL30967880 | 0.79 | FFAR1 (0.51) | CYP4F2CYP4A11FFAR1KDM1AMAOA | |
| SCHEMBL5478594 | 0.76 | POLB (0.52) | CYP4F2CYP4A11KDM1A | |
| SCHEMBL25169879 | 0.76 | FFAR1 (0.50) | FFAR1SLC9A1HDAC4 | |
| SCHEMBL29302377 | 0.76 | AKR1C3 (0.51) | FFAR1SLC9A1HDAC4 | |
| SCHEMBL4775489 | 0.76 | FFAR1 (0.50) | FFAR1SLC9A1HDAC4 | |
| SCHEMBL28669621 | 0.76 | FFAR1 (0.50) | FFAR1SLC9A1HDAC4 | |
| SCHEMBL24739852 | 0.76 | AKR1C3 (0.51) | FFAR1SLC9A1HDAC4 | |
| SCHEMBL28678691 | 0.76 | FFAR1 (0.50) | FFAR1SLC9A1HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007516982-A | — | — | 2007-06-28 | — | — | JP | claimed |
| EP-1694410-A2 | CYCLOPROPANE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | Japan Tobacco, Inc. (JP) | 2006-08-30 | — | — | EP | claimed |
| WO-2005058884-A2 | CYCLOPROPANE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2005-06-30 | — | — | WO | claimed |