Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25169879 | 1.00 | FFAR1 (0.50) | FFAR1HTR2AHTR2CHTR2BCHRNB4 | |
| SCHEMBL4775489 | 1.00 | FFAR1 (0.50) | FFAR1HTR2AHTR2CHTR2BCHRNB4 | |
| SCHEMBL28669621 | 1.00 | FFAR1 (0.50) | FFAR1HTR2AHTR2CHTR2BCHRNB4 | |
| SCHEMBL8013432 | 0.83 | MGLL (0.46) | HTR2AHTR2CHTR2BCHRNB4CHRNA3 | |
| SCHEMBL29302377 | 0.82 | AKR1C3 (0.51) | FFAR1HDAC4ALDH1A1SLC9A1 | |
| SCHEMBL24739852 | 0.82 | AKR1C3 (0.51) | FFAR1HDAC4ALDH1A1SLC9A1 | |
| SCHEMBL6934584 | 0.81 | CHRNB4 (0.48) | HTR2AHTR2CHTR2BCHRNB4CHRNA3 | |
| SCHEMBL23116570 | 0.81 | FFAR1 (0.65) | FFAR1HTR2AHTR2CHTR2BHDAC4 | |
| SCHEMBL4134734 | 0.81 | KDM1A (0.56) | FFAR1HTR2AHTR2CHTR2BHDAC4 | |
| SCHEMBL24737484 | 0.81 | SLC9A1 (0.64) | FFAR1HTR2AHTR2CHTR2BHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113614089-A | Novel morphinans useful for treating medical conditions | 人福医药美国公司 | 2021-11-05 | — | — | CN | disclosed |