SCHEMBL5487310

SCHEMBL5487310

CCCCCCCCCCCCCCCCCCCCNC(C)N(C)C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 8/20 0.42
ALDH1A1 P00352 3/20 0.40
TSHR P16473 3/20 0.40
KDM4E B2RXH2 1/20 0.39
ADH1B P00325 1/20 0.38
ADH1C P00326 1/20 0.38
ADH1A P07327 1/20 0.38
ADH4 P08319 1/20 0.38
ADH7 P40394 1/20 0.38
DNM1 Q05193 3/20 0.37
THRB P10828 1/20 0.36
SPHK1 Q9NYA1 1/20 0.35
LMNA P02545 2/20 0.35
MEN1 O00255 1/20 0.35
XBP1 P17861 1/20 0.35
KMT2A Q03164 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
ABCB11 O95342 1/20 0.35
EGFR P00533 1/20 0.35
ESR1 P03372 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27497784 1.00 EPHX1 (0.42) EPHX1ALDH1A1TSHRKDM4EADH1B
SCHEMBL27498119 1.00 EPHX1 (0.42) EPHX1ALDH1A1TSHRKDM4EADH1B
SCHEMBL29009611 1.00 EPHX1 (0.42) EPHX1ALDH1A1TSHRKDM4EADH1B
SCHEMBL6398657 1.00 EPHX1 (0.42) EPHX1ALDH1A1TSHRKDM4EADH1B
SCHEMBL27446180 1.00 EPHX1 (0.42) EPHX1ALDH1A1TSHRKDM4EADH1B
SCHEMBL29009616 1.00 EPHX1 (0.42) EPHX1ALDH1A1TSHRKDM4EADH1B
SCHEMBL15159800 1.00 EPHX1 (0.42) EPHX1ALDH1A1TSHRKDM4EADH1B
SCHEMBL27446710 0.98 ALDH1A1 (0.42) EPHX1ALDH1A1TSHRKDM4EADH1B
SCHEMBL15591672 0.91 TSHR (0.36) ALDH1A1TSHRKDM4EADH1BADH1C
SCHEMBL28988992 0.80 EPHX1 (0.41) EPHX1ALDH1A1TSHRKDM4EADH1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3634369-B1 METHODS FOR TREATING CHEMICALLY RELAXED HAIR OREAL (FR) 2023-10-25 EP claimed
CN-112771207-A Oil and gas field corrosion inhibitor composition 花王株式会社 2021-05-07 CN disclosed
EP-1723972-B1 Vectorisation of dsRNA by cationic particles and their use for the production of a skin model L'ORÉAL (FR) 2018-01-24 EP disclosed
EP-1774959-B1 DOUBLE STRANDED RNA OLIGONUCLEOTIDE FOR THE INHIBITION OF TYROSINASE EXPRESSION L'ORÉAL (FR) 2018-01-24 EP disclosed
EP-1774959-A1 Double stranded RNA oligonucleotide to inhibit tyrosinase expression L'Oréal (FR) 2007-04-18 EP disclosed
EP-1723958-A2 dsRNA vectorisation with cationic particles and their topical use L'OREAL (FR) 2006-11-22 EP disclosed
EP-1723972-A1 Vectorisation of dsRNA by cationic particles and their use in a skin model L'OREAL (FR) 2006-11-22 EP disclosed