SCHEMBL6398657

SCHEMBL6398657

CCCCCCCCCCCCCCCCCCNC(C)N(C)C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 8/20 0.42
ALDH1A1 P00352 3/20 0.40
TSHR P16473 3/20 0.40
KDM4E B2RXH2 1/20 0.39
ADH1B P00325 1/20 0.38
ADH1C P00326 1/20 0.38
ADH1A P07327 1/20 0.38
ADH4 P08319 1/20 0.38
ADH7 P40394 1/20 0.38
DNM1 Q05193 3/20 0.37
THRB P10828 1/20 0.36
SPHK1 Q9NYA1 1/20 0.35
LMNA P02545 2/20 0.35
MEN1 O00255 1/20 0.35
XBP1 P17861 1/20 0.35
KMT2A Q03164 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
ABCB11 O95342 1/20 0.35
EGFR P00533 1/20 0.35
ESR1 P03372 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27497784 1.00 EPHX1 (0.42) EPHX1ALDH1A1TSHRKDM4EADH1B
SCHEMBL27498119 1.00 EPHX1 (0.42) EPHX1ALDH1A1TSHRKDM4EADH1B
SCHEMBL29009611 1.00 EPHX1 (0.42) EPHX1ALDH1A1TSHRKDM4EADH1B
SCHEMBL5487310 1.00 EPHX1 (0.42) EPHX1ALDH1A1TSHRKDM4EADH1B
SCHEMBL27446180 1.00 EPHX1 (0.42) EPHX1ALDH1A1TSHRKDM4EADH1B
SCHEMBL29009616 1.00 EPHX1 (0.42) EPHX1ALDH1A1TSHRKDM4EADH1B
SCHEMBL15159800 1.00 EPHX1 (0.42) EPHX1ALDH1A1TSHRKDM4EADH1B
SCHEMBL27446710 0.98 ALDH1A1 (0.42) EPHX1ALDH1A1TSHRKDM4EADH1B
SCHEMBL15591672 0.91 TSHR (0.36) ALDH1A1TSHRKDM4EADH1BADH1C
SCHEMBL28988992 0.80 EPHX1 (0.41) EPHX1ALDH1A1TSHRKDM4EADH1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050002887-A1 Cosmetic composition comprising at least one branched sulphonic polyester and at least one conditioning agent L'OREAL S.A. 2005-01-06 US claimed
EP-0966946-B1 Cosmetic composition at least containing a branched sulfonic polyester and a conditioning agent OREAL (FR) 2004-11-10 EP claimed
EP-0920859-B1 Aqueous dispersion containing as UV-filter an organopolysiloxane functionalised with benzalmalonate and a water insoluble cationic tensid OREAL (FR) 2001-04-11 EP claimed
EP-0966946-A1 Cosmetic composition at least containing a branched sulfonic polyester and a conditioning agent L'OREAL (FR) 1999-12-29 EP claimed
EP-0920859-A1 Aqueous dispersion containing as UV-filter an organopolysiloxane functionalised with benzalmalonate and a water insoluble cationic tensid L'OREAL (FR) 1999-06-09 EP claimed
CN-118085275-A Conditioning fluffy composition and application thereof in personal care products 广州慕可生物科技有限公司 2024-05-28 CN disclosed
CN-115999479-A Production system and preparation method for continuously producing salt-free amphoteric surfactant 岳阳科罗德联合化学工业有限公司 2023-04-25 CN disclosed
CN-101511335-B Hair treatment compositions incorporating hair substantive polymers UNILEVER NV 2013-07-31 CN disclosed
CN-101583343-A hair conditioning composition UNILEVER PLC (NL) 2009-11-18 CN disclosed
CN-101511335-A Hair treatment compositions incorporating hair substantive polymers UNILEVER PLC (NL) 2009-08-19 CN disclosed
CN-100479802-C Hair treatment compositions UNILEVER PLC (NL) 2009-04-22 CN disclosed
CN-1964693-A Hair treatment compositions UNILEVER PLC (NL) 2007-05-16 CN disclosed
US-20050002887-A1 Cosmetic composition comprising at least one branched sulphonic polyester and at least one conditioning agent L'OREAL S.A. 2005-01-06 US disclosed
EP-1319391-A1 Cosmetic composition containing at least one silicone/acrylate copolymer and at least one conditioning agent L'OREAL (FR) 2003-06-18 EP disclosed
EP-0920859-B1 Aqueous dispersion containing as UV-filter an organopolysiloxane functionalised with benzalmalonate and a water insoluble cationic tensid OREAL (FR) 2001-04-11 EP disclosed
EP-1084694-A1 Cosmetic composition containing at least a silicone/acrylate copolymer and at least a conditioning agent L'OREAL (FR) 2001-03-21 EP disclosed
US-6120757-A COSMETICS; THERAPY FOR SKIN DISORDERS, HAIR SOCIETE L'OREAL S.A. (FR) 2000-09-19 US disclosed
EP-0966946-A1 Cosmetic composition at least containing a branched sulfonic polyester and a conditioning agent L'OREAL (FR) 1999-12-29 EP disclosed
EP-0920859-A1 Aqueous dispersion containing as UV-filter an organopolysiloxane functionalised with benzalmalonate and a water insoluble cationic tensid L'OREAL (FR) 1999-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050002887-A1 Cosmetic composition comprising at least one branched sulphonic polyester and at least one conditioning agent KRT18, FHIT, CUTA EPHX1 4535/4885ALDH1A1 3947/4885TSHR 2828/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.