Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK2 | O95069 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.39 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 2/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4761229 | 0.88 | SLC6A2 (0.50) | KCNK2SLC6A4SLC6A2 | |
| SCHEMBL4717810 | 0.88 | SLC6A2 (0.50) | KCNK2SLC6A4SLC6A2 | |
| SCHEMBL4078606 | 0.88 | SLC6A4 (0.44) | KCNK2SLC6A4SLC6A2TP53 | |
| SCHEMBL4763037 | 0.88 | SLC6A2 (0.48) | SLC6A4SLC6A2PTGDR2 | |
| Hydrochloric Acid SCHEMBL5481020 | 0.87 | SLC6A2 (0.49) | KCNK2SLC6A4SLC6A2 | |
| SCHEMBL4080539 | 0.87 | SLC6A4 (0.56) | SLC6A4SLC6A2C5AR1 | |
| SCHEMBL4080079 | 0.86 | SLC6A4 (0.55) | SLC6A4SLC6A2C5AR1 | |
| SCHEMBL4718299 | 0.85 | SLC6A2 (0.44) | SLC6A4SLC6A2PTGDR2 | |
| SCHEMBL4717986 | 0.85 | SLC6A4 (0.42) | SLC6A4SLC6A2PGR | |
| SCHEMBL4086791 | 0.83 | SLC6A4 (0.52) | SLC6A4SLC6A2C5AR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070072897-A1 | Phenylaminopropanol derivatives and methods of their use | WYETH (US) | 2007-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070072897-A1 | Phenylaminopropanol derivatives and methods of their use | COMT, PNMT, GLS | KCNK2 1792/4885SLC6A4 16/4885SLC6A2 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.