SCHEMBL5487497

SCHEMBL5487497

CCOC(CCCl)[SiH](C)C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.33
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3583963 0.78 THRB (0.35) THRBLMNA
SCHEMBL538097 0.76 MEN1 (0.34) THRBLMNA
SCHEMBL557064 0.74 THRB (0.32) THRBLMNA
SCHEMBL671566 0.74 THRB (0.32) THRBLMNA
Hydrogen Sulfide SCHEMBL27628151 0.72 THRB (0.38) THRBLMNA
SCHEMBL444238 0.71
SCHEMBL15240221 0.71
SCHEMBL1583116 0.70
SCHEMBL10613074 0.70
SCHEMBL57500 0.69 THRB (0.40) THRBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1515977-B1 METHOD OF PREPARING ORGANO DIALKYLALKOXYSILANE RHODIA CHIMIE SA (FR) 2007-08-29 EP disclosed
EP-1515977-A1 METHOD OF PREPARING ORGANO DIALKYLALKOXYSILANE Rhodia Chimie SA (FR) 2005-03-23 EP disclosed
WO-2004000852-A1 METHOD OF PREPARING ORGANO DIALKYLALKOXYSILANE RHODIA CHIMIE SA (FR) 2003-12-31 WO disclosed