Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.60 |
| ▸ | HPGD | P15428 | 7/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5487521 | 1.00 | ALDH1A1 (0.60) | ALDH1A1HPGDKDM4EGAASMN1; SMN2 | |
| SCHEMBL5497181 | 0.95 | ALDH1A1 (0.58) | ALDH1A1HPGDKDM4EGAASMN1; SMN2 | |
| SCHEMBL5497176 | 0.95 | ALDH1A1 (0.58) | ALDH1A1HPGDKDM4EGAASMN1; SMN2 | |
| SCHEMBL5494892 | 0.89 | ALDH1A1 (0.58) | ALDH1A1HPGDKDM4EGAASMN1; SMN2 | |
| SCHEMBL5494884 | 0.89 | ALDH1A1 (0.58) | ALDH1A1HPGDKDM4EGAASMN1; SMN2 | |
| SCHEMBL11462114 | 0.84 | TRPV1 (0.70) | ALDH1A1HPGDKDM4EGAASMN1; SMN2 | |
| SCHEMBL11462115 | 0.84 | TRPV1 (0.70) | ALDH1A1HPGDKDM4EGAASMN1; SMN2 | |
| SCHEMBL11434941 | 0.84 | TRPV1 (0.70) | ALDH1A1HPGDKDM4EGAASMN1; SMN2 | |
| SCHEMBL17340453 | 0.84 | TRPV1 (0.70) | ALDH1A1HPGDKDM4EGAASMN1; SMN2 | |
| SCHEMBL5495380 | 0.82 | TRPV1 (0.71) | ALDH1A1HPGDKDM4EGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140073595-A1 | AROMATIC AMIDES AS POTENTIATORS OF BIOEFFICACY OF ANTI-INFECTIVE DRUGS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2014-03-13 | — | — | US | claimed |
| US-8580752-B2 | Aromatic amides as potentiators of bioefficacy of anti-infective drugs | COUNCIL OF SCIENTITIC AND INDUSTRIAL RESEARCH (IN) | 2013-11-12 | — | — | US | claimed |
| US-20070004645-A1 | Aromatic amides as potentiators of bioefficacy of anti-infective drugs | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-01-04 | — | — | US | claimed |
| US-9073860-B2 | Aromatic amides as potentiators of bioefficacy of anti-infective drugs | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2015-07-07 | — | — | US | disclosed |
| US-20140073595-A1 | AROMATIC AMIDES AS POTENTIATORS OF BIOEFFICACY OF ANTI-INFECTIVE DRUGS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2014-03-13 | — | — | US | disclosed |
| US-8580752-B2 | Aromatic amides as potentiators of bioefficacy of anti-infective drugs | COUNCIL OF SCIENTITIC AND INDUSTRIAL RESEARCH (IN) | 2013-11-12 | — | — | US | disclosed |
| US-20070004645-A1 | Aromatic amides as potentiators of bioefficacy of anti-infective drugs | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140073595-A1 | AROMATIC AMIDES AS POTENTIATORS OF BIOEFFICACY OF ANTI-INFECTIVE DRUGS | DDC, APEH, AADAC | ALDH1A1 265/4885HPGD 115/4885KDM4E 1523/4885 |
| US-20070004645-A1 | Aromatic amides as potentiators of bioefficacy of anti-infective drugs | DDC, APEH, AADAC | ALDH1A1 265/4885HPGD 115/4885KDM4E 1523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.