Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 15/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26277654 | 0.81 | ABCB1 (0.39) | ABCB1BCHE | |
| SCHEMBL20227072 | 0.81 | ALDH1A1 (0.40) | ABCB1BCHE | |
| SCHEMBL5487793 | 0.80 | ABCB1 (0.44) | ABCB1BCHE | |
| SCHEMBL5487798 | 0.80 | ABCB1 (0.44) | ABCB1BCHE | |
| SCHEMBL5492143 | 0.79 | MAPT (0.48) | ABCB1BCHE | |
| SCHEMBL5492148 | 0.79 | MAPT (0.48) | ABCB1BCHE | |
| SCHEMBL7152559 | 0.79 | ABCB1 (0.43) | ABCB1BCHE | |
| SCHEMBL11398254 | 0.79 | ABCB1 (0.43) | ABCB1BCHE | |
| SCHEMBL7149873 | 0.79 | ABCB1 (0.43) | ABCB1BCHE | |
| SCHEMBL26290153 | 0.79 | LMNA (0.44) | GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023178133-A9 | COMPOUNDS AND METHODS FOR TREATING DISEASE | ROME THERAPEUTICS, INC. (US) | 2023-10-26 | — | — | WO | disclosed |
| WO-2023178133-A1 | COMPOUNDS AND METHODS FOR TREATING DISEASE | ROME THERAPEUTICS, INC. (US) | 2023-09-21 | — | — | WO | disclosed |