SCHEMBL5487858

SCHEMBL5487858

C=Cc1ccccc1CC[Si](Cl)(Cl)Cl

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.42
MITF O75030 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7038514 0.85 ALDH1A1 (0.39) ALDH1A1MITF
SCHEMBL9081052 0.85 ALDH1A1 (0.39) ALDH1A1MITF
SCHEMBL595200 0.81 ALDH1A1 (0.48) ALDH1A1MITF
SCHEMBL29377653 0.81 ALDH1A1 (0.48) ALDH1A1MITF
SCHEMBL7037729 0.80 ALDH1A1 (0.45) ALDH1A1
SCHEMBL5072509 0.79 ALDH1A1 (0.46) ALDH1A1MITF
SCHEMBL765987 0.79 TAAR1 (0.36)
SCHEMBL30997335 0.79 TAAR1 (0.36)
SCHEMBL810100 0.78 ALDH1A1 (0.46) ALDH1A1MITF
SCHEMBL6278153 0.77 ALDH1A1 (0.44) ALDH1A1MITF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7291747-B2 Silicon compounds and process for preparation thereof CHISSO CORPORATION (JP) 2007-11-06 US disclosed
US-20040143081-A1 Novel silicon compounds and process for preparation thereof JNC CORPORATION (JP) 2004-07-22 US disclosed
EP-0816419-B9 Ultraviolet-curable polysiloxane composition and method for the formation of cured patterns therefrom DOW CORNING ASIA LTD (JP) 2003-10-22 EP disclosed
EP-0816419-B1 Ultraviolet-curable polysiloxane composition and method for the formation of cured patterns therefrom DOW CORNING ASIA LTD (JP) 2003-03-12 EP disclosed
US-6258506-B1 USING BLEND OF BENZOIN ETHER AND FREE RADICAL POLYMERIZABLE SILICONE POLYMER DOW CORNING ASIA, LTD. (JP) 2001-07-10 US disclosed
US-6051625-A Ultraviolet-curable polysiloxane composition and method for the formation of cured patterns therefrom DOW CORNING ASIA, LTD. (JP) 2000-04-18 US disclosed
EP-0816419-A2 Ultraviolet-curable polysiloxane composition and method for the formation of cured patterns therefrom DOW CORNING ASIA, Ltd. (JP) 1998-01-07 EP disclosed
US-5098981-A POLYORGANOSILOXANE CHISSO CORPORATION (JP) 1992-03-24 US disclosed
EP-0349920-A2 Polyorganosiloxane Chisso Corporation (JP) 1990-01-10 EP disclosed
US-4202812-A CURED ELASTOMERS WITH IMPROVED TENSILE STRENGTH DOW CORNING CORPORATION (US) 1980-05-13 US disclosed