SCHEMBL765987

SCHEMBL765987

Cl[Si](Cl)(Cl)CCc1ccccc1CC[Si](Cl)(Cl)Cl

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 8/20 0.36
IDO1 P14902 2/20 0.33
PNMT P11086 1/20 0.33
HTR2A P28223 1/20 0.33
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
HSPA5 P11021 1/20 0.31
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
SLC6A3 Q01959 1/20 0.30
AOC3 Q16853 1/20 0.30
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30997335 1.00 TAAR1 (0.36) TAAR1IDO1PNMTHTR2ANPC1
SCHEMBL3224942 0.91 ALDH1A1 (0.36) TAAR1
SCHEMBL5487166 0.85 TAAR1 (0.56) TAAR1IDO1PNMTNPC1RAB9A
SCHEMBL6673171 0.84 TAAR1 (0.54) TAAR1
SCHEMBL3799104 0.80 MTNR1A (0.49)
SCHEMBL1033573 0.79 TAAR1 (0.34) TAAR1IDO1PNMTHTR2ASLC6A2
SCHEMBL15544091 0.79 TAAR1 (0.34) TAAR1IDO1PNMTHTR2ASLC6A2
SCHEMBL5487858 0.79 ALDH1A1 (0.42)
SCHEMBL1970395 0.79 TAAR1 (0.58) TAAR1IDO1AOC3KCNH2
SCHEMBL1162375 0.77 ALDH1A1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250075102-A1 COMPOUNDS COMPRISING A PLURALITY OF SILSEQUIOXANE GROUPS FOR FORMING A PATTERNING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2025-03-06 US disclosed
WO-2023119165-A9 COMPOUNDS COMPRISING A PLURALITY OF SILSESQUIOXANE GROUPS FOR FORMING A PATTERNING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2024-04-04 WO disclosed
WO-2023119165-A1 COMPOUNDS COMPRISING A PLURALITY OF SILSESQUIOXANE GROUPS FOR FORMING A PATTERNING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-06-29 WO disclosed
EP-3938412-A1 MODIFIED HIGH CIS POLYDIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS BRIDGESTONE CORPORATION (JP) 2022-01-19 EP disclosed
WO-2020185761-A1 MODIFIED HIGH CIS POLYDIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS BRIDGESTONE CORPORATION (JP) 2020-09-17 WO disclosed
EP-2251365-B1 Crosslinkable polyolefin composition comprising silane groups forming an acid or a base upon hydrolysation BOREALIS AG (AT) 2018-11-07 EP disclosed
US-8846844-B2 Crosslinkable polyolefin composition comprising silane groups forming an acid or a base upon hydrolysation BOREALIS AG (AT) 2014-09-30 US disclosed
US-20120071607-A1 CROSSLINKABLE POLYOLEFIN COMPOSITION COMPRISING SILANE GROUPS FORMING AN ACID OR A BASE UPON HYDROLYSATION BOREALIS AG (AT) 2012-03-22 US disclosed
WO-2010130458-A1 CROSSLINKABLE POLYOLEFIN COMPOSITION COMPRISING SILANE GROUPS FORMING AN ACID OR A BASE UPON HYDROLYSATION BOREALIS AG (AT) 2010-11-18 WO disclosed
EP-2251365-A1 Crosslinkable polyolefin composition comprising silane groups forming an acid or a base upon hydrolysation Borealis AG (AT) 2010-11-17 EP disclosed
US-20040082803-A1 Trichlorosilyl groups containing organochlorosilanes and their preparation methods by the double-silylation of olefins with trichlorosilane KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY 2004-04-29 US disclosed
US-5726336-A REACTING A BENZENE COMPOUND WITH A VINYLCHLOROSILANE COMPOUND IN THE PRESENCE OF A LEWIS ACID CATALYST; INTERMEDIATES FOR SILICONE POLYMERS USEFUL AS EMULSIONS, GREASES, ADHESIVES, SEALANTS, COATINGS, IN AUTOMOTIVE AND ENGINEERING FIELDS KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 1998-03-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040082803-A1 Trichlorosilyl groups containing organochlorosilanes and their preparation methods by the double-silylation of olefins with trichlorosilane CBR1, OXSR1, HCCS TAAR1 123/4885IDO1 1912/4885PNMT 2121/4885
US-20120071607-A1 CROSSLINKABLE POLYOLEFIN COMPOSITION COMPRISING SILANE GROUPS FORMING AN ACID OR A BASE UPON HYDROLYSATION HRH2, GLRA2, ACTR2 TAAR1 662/4885IDO1 4702/4885PNMT 1607/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.