SCHEMBL5487986

SCHEMBL5487986

COC(=O)C(Cl)c1ccc(Cl)c(Cl)c1

nearest known ligand 0.57

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 9/20 0.57
SLC6A2 P23975 2/20 0.52
SLC6A4 P31645 2/20 0.52
ALDH1A1 P00352 1/20 0.47
LMNA P02545 1/20 0.47
HTT P42858 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11001290 0.84 SLC6A3 (0.59) SLC6A3SLC6A2SLC6A4ALDH1A1LMNA
SCHEMBL924713 0.83 SLC6A3 (0.48) SLC6A3SLC6A2SLC6A4ALDH1A1LMNA
SCHEMBL1566494 0.82 SLC6A3 (0.57) SLC6A3SLC6A2SLC6A4ALDH1A1LMNA
SCHEMBL1566492 0.82 SLC6A3 (0.57) SLC6A3SLC6A2SLC6A4ALDH1A1LMNA
SCHEMBL1626214 0.82 SLC6A3 (0.57) SLC6A3SLC6A2SLC6A4ALDH1A1LMNA
SCHEMBL28541577 0.81 SLC6A3 (0.43) SLC6A3SLC6A2SLC6A4ALDH1A1LMNA
SCHEMBL11776193 0.81 SLC6A3 (0.47) SLC6A3SLC6A2SLC6A4ALDH1A1LMNA
SCHEMBL9395161 0.81 SLC6A3 (0.56) SLC6A3SLC6A2SLC6A4ALDH1A1LMNA
SCHEMBL6988620 0.81 SLC6A3 (0.56) SLC6A3SLC6A2SLC6A4ALDH1A1LMNA
SCHEMBL30522901 0.81 SLC6A3 (0.56) SLC6A3SLC6A2SLC6A4ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7256158-B2 2,4,5,-trisubstituted phenylketo-enols for use as pesticides and herbicides BAYER AG (DE) 2007-08-14 US disclosed
US-6933261-B2 2,4,5-Trisubstituted phenylketoenols BAYER AKTIENGESELLSCHAFT (DE) 2005-08-23 US disclosed
US-20050038021-A1 2,4,5,-trisubstituted phenylketo-enols for use as pesticides and herbicides BAYER AG (DE) 2005-02-17 US disclosed
US-20030171219-A1 2,4,5-trisubstituted phenylketo-enols for use as pesticides and herbicides LIEB FOLKER (DE) 2003-09-11 US disclosed
US-6511942-B1 Animal husbandry, veterinary medicine BAYER AKTIENGESELLSCHAFT (DE) 2003-01-28 US disclosed
US-6110872-A 3-(2,4,5-TRISUBSTITUTED PHENYL), 4-HYDROXY,5,5-(CYCLOALKYL OR HETEROCYCLOALKYL)PYRROLIN-2-ONE AND DERIVATIVES; METHOD OF MAKING BY INTRAMOLECULAR CONDENSATION OF SPECIFIED COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 2000-08-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050038021-A1 2,4,5,-trisubstituted phenylketo-enols for use as pesticides and herbicides DDT, CYP4X1, PDHX SLC6A3 3576/4885SLC6A2 4543/4885SLC6A4 3672/4885
US-20030171219-A1 2,4,5-trisubstituted phenylketo-enols for use as pesticides and herbicides DDT, CYP4X1, HPD SLC6A3 4042/4885SLC6A2 4627/4885SLC6A4 4118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.