Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 10/20 | 0.84 |
| ▸ | NR3C1 | P04150 | 8/20 | 0.84 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.84 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.84 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.84 |
| ▸ | PGR | P06401 | 2/20 | 0.84 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.84 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.84 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.84 |
| ▸ | MAPT | P10636 | 2/20 | 0.84 |
| ▸ | SHBG | P04278 | 1/20 | 0.84 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.84 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.84 |
| ▸ | LMNA | P02545 | 2/20 | 0.78 |
| ▸ | AR | P10275 | 1/20 | 0.77 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.77 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19327149 | 1.00 | HIF1A (0.84) | HIF1ANR3C1SMN1; SMN2CYP2C19HSD17B10 | |
| SCHEMBL4983 | 1.00 | HIF1A (0.84) | HIF1ANR3C1SMN1; SMN2CYP2C19HSD17B10 | |
| Hydrocortisone SCHEMBL19465688 | 0.91 | HIF1A (1.00) | HIF1ANR3C1SMN1; SMN2CYP2C19HSD17B10 | |
| SCHEMBL22476662 | 0.91 | HIF1A (0.85) | HIF1ANR3C1SMN1; SMN2CYP2C19HSD17B10 | |
| Hydrocortisone SCHEMBL1560948 | 0.91 | HIF1A (1.00) | HIF1ANR3C1SMN1; SMN2CYP2C19HSD17B10 | |
| Hydrocortisone SCHEMBL24900238 | 0.91 | HIF1A (1.00) | HIF1ANR3C1SMN1; SMN2CYP2C19HSD17B10 | |
| Hydrocortisone SCHEMBL6932400 | 0.91 | HIF1A (1.00) | HIF1ANR3C1SMN1; SMN2CYP2C19HSD17B10 | |
| SCHEMBL14513165 | 0.91 | HIF1A (0.85) | HIF1ANR3C1SMN1; SMN2CYP2C19HSD17B10 | |
| Hydrocortisone SCHEMBL143923 | 0.91 | HIF1A (1.00) | HIF1ANR3C1SMN1; SMN2CYP2C19HSD17B10 | |
| Hydrocortisone SCHEMBL1688689 | 0.91 | HIF1A (1.00) | HIF1ANR3C1SMN1; SMN2CYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070021360-A1 | Compositions, formulations and kit with anti-sense oligonucleotide and anti-inflammatory steroid and/or obiquinone for treatment of respiratory and lung disesase | EPIGENESIS PHARMACEUTICALS, LLC | 2007-01-25 | — | — | US | claimed |
| EP-1200096-B1 | TIXOCORTOL PIVALATE SUSPENSION, MOUTH-WASH BASED THEREON AND PACKAGING CONTAINING SAME | WARNER LAMBERT CO (US) | 2004-06-16 | — | — | EP | disclosed |
| EP-0452914-B1 | 21-Substituted pregnane derivatives | KAO CORP (JP) | 1996-07-10 | — | — | EP | disclosed |
| US-5116829-A | 21-Substituted, Antiinflammatory Agents, Antiallergens, Rheumatism | KAO CORPORATION (JP) | 1992-05-26 | — | — | US | disclosed |
| EP-0452914-A2 | 21-Substituted pregnane derivatives | KAO CORPORATION (JP) | 1991-10-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021360-A1 | Compositions, formulations and kit with anti-sense oligonucleotide and anti-inflammatory steroid and/or obiquinone for treatment of respiratory and lung disesase | RECQL, GSS, DDX17 | HIF1A 1076/4885NR3C1 104/4885SMN1; SMN2 3963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.