Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.57 |
| ▸ | RELA | Q04206 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | C1S | P09871 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5488350 | 0.94 | SMN1; SMN2 (0.61) | PARP1HPGDSMN1; SMN2GAANFKB1 | |
| SCHEMBL27597152 | 0.88 | PARP1 (0.53) | PARP1HPGDSMN1; SMN2GAANFKB1 | |
| SCHEMBL7655031 | 0.87 | PARP1 (0.61) | PARP1HPGDSMN1; SMN2GAANFKB1 | |
| SCHEMBL247378 | 0.85 | PARP1 (0.64) | PARP1HPGDSMN1; SMN2GAANFKB1 | |
| SCHEMBL28681117 | 0.84 | SMN1; SMN2 (0.64) | PARP1HPGDSMN1; SMN2GAANFKB1 | |
| SCHEMBL8674123 | 0.83 | MEN1 (0.59) | GAACYP1A2ALDH1A1TP53TSHR | |
| SCHEMBL514262 | 0.83 | PARP1 (0.57) | PARP1HPGDSMN1; SMN2GAANFKB1 | |
| SCHEMBL29818019 | 0.83 | KDM4E (0.59) | PARP1HPGDSMN1; SMN2GAANFKB1 | |
| SCHEMBL27030553 | 0.83 | PARP1 (0.62) | PARP1HPGDSMN1; SMN2GAANFKB1 | |
| SCHEMBL145700 | 0.83 | KDM4E (0.59) | PARP1HPGDSMN1; SMN2GAANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114995060-B | Negative photosensitive resin composition capable of being cured at low temperature and preparation method and application thereof | 明士(北京)新材料开发有限公司 | 2022-11-01 | — | — | CN | claimed |
| CN-114995060-A | Negative photosensitive resin composition capable of being cured at low temperature and preparation method and application thereof | 明士(北京)新材料开发有限公司 | 2022-09-02 | — | — | CN | claimed |
| CN-110698659-B | Phthalic anhydride polyester polyol and preparation method thereof | 万华化学集团股份有限公司 | 2022-04-22 | — | — | CN | claimed |
| CN-114230792-A | Positive photosensitive polyimide resin, resin composition, and preparation method and application thereof | 明士(北京)新材料开发有限公司 | 2022-03-25 | — | — | CN | claimed |
| CN-112745492-A | Polyester polyol for polyurethane hot melt adhesive and preparation method and application thereof | 万华化学集团股份有限公司 | 2021-05-04 | — | — | CN | claimed |
| CN-111635526-B | Polyether imide polymer containing carboxyl side group and preparation method and application thereof | 吉林大学 | 2021-03-23 | — | — | CN | claimed |
| CN-111635526-A | Polyether imide polymer containing carboxyl side group and preparation method and application thereof | 吉林大学 | 2020-09-08 | — | — | CN | claimed |
| CN-110951076-A | Hyperbranched polyetherimide and preparation and application thereof | 北京化工大学 | 2020-04-03 | — | — | CN | claimed |
| CN-110698659-A | Phthalic anhydride polyester polyol and preparation method thereof | 万华化学集团股份有限公司 | 2020-01-17 | — | — | CN | claimed |
| US-7247740-B2 | Reacting perfluoroalkanesulfonic acid directly with dialkyl carbonate to give alkyl perfluoroalkanesulfonate optionally in the presence of a water or alcohol consuming reagent, and preparing an alkyl perfluoroalkanesulfonate with an alkylamine or alkylphosphine to prepare perfluoroalkanesulfonic acid | MERCK PATENT GMBH (DE) | 2007-07-24 | — | — | US | claimed |
| EP-1472217-B1 | METHOD FOR PRODUCING PERFLUOROALKANE SULFONIC ACID ESTERS AND THE SALTS THEREOF | MERCK PATENT GMBH (DE) | 2007-01-24 | — | — | EP | claimed |
| US-20050085655-A1 | Reacting perfluoroalkanesulfonic acid directly with dialkyl carbonate to give alkyl perfluoroalkanesulfonate optionally in the presence of a water or alcohol consuming reagent, and preparing an alkyl perfluoroalkanesulfonate with an alkylamine or alkylphosphine to prepare perfluoroalkanesulfonic acid | MERCK PATENT GMBH (DE) | 2005-04-21 | — | — | US | claimed |
| CN-114995060-B | Negative photosensitive resin composition capable of being cured at low temperature and preparation method and application thereof | 明士(北京)新材料开发有限公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-115236938-A | Negative photosensitive polyamic acid ester resin composition and use thereof | 明士(北京)新材料开发有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-114995060-A | Negative photosensitive resin composition capable of being cured at low temperature and preparation method and application thereof | 明士(北京)新材料开发有限公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-110698659-B | Phthalic anhydride polyester polyol and preparation method thereof | 万华化学集团股份有限公司 | 2022-04-22 | — | — | CN | disclosed |
| US-4018787-A | HERBICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1977-04-19 | — | — | US | disclosed |
| US-4006009-A | 1-Thiadiazolyl-6-acyloxytetrahydropyrimidinone herbicides | VELSICOL CHEMICAL CORPORATION (US) | 1977-02-01 | — | — | US | disclosed |
| US-4004912-A | 1-Thiadiazolyl-6-acyloxytetrahydropyrimidinone herbicides | VELSICOL CHEMICAL CORPORATION (US) | 1977-01-25 | — | — | US | disclosed |
| US-3970671-A | XANTHENE, PRESSURE SENSITIVE | KANZAKI PAPER MANUFACTURING CO., LTD. (JA) | 1976-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050085655-A1 | Reacting perfluoroalkanesulfonic acid directly with dialkyl carbonate to give alkyl perfluoroalkanesulfonate optionally in the presence of a water or alcohol consuming reagent, and preparing an alkyl perfluoroalkanesulfonate with an alkylamine or alkylphosphine to prepare perfluoroalkanesulfonic acid | PFKFB2, PFKFB3, PHOSPHO1 | PARP1 1050/4885HPGD 3924/4885SMN1; SMN2 4651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.