Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.57 |
| ▸ | RELA | Q04206 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | C1S | P09871 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5488346 | 0.87 | PARP1 (0.61) | PARP1HPGDGAANFKB1NFKB2 | |
| SCHEMBL247378 | 0.85 | PARP1 (0.64) | PARP1HPGDGAANFKB1NFKB2 | |
| SCHEMBL7655531 | 0.85 | LMNA (0.51) | PARP1HPGDCYP1A2MAPK1KDM4E | |
| SCHEMBL145700 | 0.83 | KDM4E (0.59) | PARP1HPGDGAANFKB1NFKB2 | |
| SCHEMBL27030553 | 0.83 | PARP1 (0.62) | PARP1HPGDGAANFKB1NFKB2 | |
| SCHEMBL29818019 | 0.83 | KDM4E (0.59) | PARP1HPGDGAANFKB1NFKB2 | |
| SCHEMBL514262 | 0.83 | PARP1 (0.57) | PARP1HPGDGAANFKB1NFKB2 | |
| SCHEMBL8387942 | 0.82 | CES2 (0.54) | HPGDGAANFKB1NFKB2RELA | |
| SCHEMBL5488350 | 0.82 | SMN1; SMN2 (0.61) | PARP1HPGDGAANFKB1NFKB2 | |
| SCHEMBL245137 | 0.80 | KDM4E (0.65) | SMN1; SMN2MAPK1KDM4ELMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4647641-A | BROMOBENZOYL PEROXIDES | PENNWALT CORPORATION (US) | 1987-03-03 | — | — | US | claimed |
| US-6491903-B1 | NARROW MOLECULAR WEIGHT DISTRIBUTION SHELL-CORE POLYMERS HAVING HYDROPHILIC, CROSSLINKED PERMEABLE SHELLS AND HYDROPHOBIC CORES, USED FOR REDUCING BLOOD CHOLESTEROL AND BILE ACID UPTAKE IN INTERSTINES; DRUG DELIVERY | WASHINGTON UNIVERSITY | 2002-12-10 | — | — | US | disclosed |
| US-6383500-B1 | Particles comprising amphiphilic copolymers, having a crosslinked shell domain and an interior core domain, useful for pharmaceutical and other applications | WASHINGTON UNIVERSITY | 2002-05-07 | — | — | US | disclosed |
| EP-0910351-A1 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. Searle & Co. (US) | 1999-04-28 | — | — | EP | disclosed |
| WO-1997049387-A1 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. SEARLE AND CO. (US) | 1997-12-31 | — | — | WO | disclosed |
| US-5547756-A | Porous polypropylene hollow fiber membrane of large pore diameter, production process thereof, and hydrophilized porous hollow fiber membranes | MITSUBISHI RAYON CO., LTD. (JP) | 1996-08-20 | — | — | US | disclosed |
| EP-0513390-B1 | POROUS HOLLOW FIBER MEMBRANE OF POLYETHYLENE AND PRODUCTION THEREOF | MITSUBISHI RAYON CO (JP) | 1996-02-14 | — | — | EP | disclosed |
| EP-0498414-B1 | Porous hollow fiber membrane of polypropylene and production thereof | MITSUBISHI RAYON CO (JP) | 1995-12-27 | — | — | EP | disclosed |
| US-5294338-A | Rectangular pores formed by microfibrils, joints of stacked lamellae and contiguous pores to form a stacked multicellur structure | MITSUBISHI RAYON CO., LTD. (JP) | 1994-03-15 | — | — | US | disclosed |
| US-5232642-A | Melt spinning, annealing | MITSUBISHI RAYON CO., LTD. (JP) | 1993-08-03 | — | — | US | disclosed |
| EP-0513390-A1 | POROUS HOLLOW FIBER MEMBRANE OF POLYETHYLENE AND PRODUCTION THEREOF | MITSUBISHI RAYON CO., LTD. (JP) | 1992-11-19 | — | — | EP | disclosed |
| EP-0498414-A2 | Porous hollow fiber membrane of polypropylene and production thereof | MITSUBISHI RAYON CO., LTD. (JP) | 1992-08-12 | — | — | EP | disclosed |
| EP-0229019-B1 | HYDROPHILIZED POROUS MEMBRANE AND PRODUCTION PROCESS THEREOF | MITSUBISHI RAYON CO., LTD. (JP) | 1991-09-18 | — | — | EP | disclosed |
| US-4876289-A | CROSSLINKED DIACETONEACRYLAMIDE PHYSICALLY HELD ON PORE WALLS OF POLYOLEFIN | MITSUBISHI RAYON CO., LTD. (JP) | 1989-10-24 | — | — | US | disclosed |
| US-4695592-A | CROSSLINKED POLYDIACETONEACRYLAMIDE | MITSUBISHI RAYON CO., LTD. (JP) | 1987-09-22 | — | — | US | disclosed |
| EP-0229019-A2 | Hydrophilized porous membrane and production process thereof | MITSUBISHI RAYON CO., LTD. (JP) | 1987-07-15 | — | — | EP | disclosed |
| US-4647641-A | BROMOBENZOYL PEROXIDES | PENNWALT CORPORATION (US) | 1987-03-03 | — | — | US | disclosed |