Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.49 |
| ▸ | C1S | P09871 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7655031 | 0.85 | PARP1 (0.61) | PARP1HPGDGAANFKB1NFKB2 | |
| SCHEMBL5488346 | 0.85 | PARP1 (0.61) | PARP1HPGDGAANFKB1NFKB2 | |
| SCHEMBL38746 | 0.84 | ATM (0.48) | PARP1LMNATSHRL3MBTL1KMT2A | |
| SCHEMBL29818019 | 0.82 | KDM4E (0.59) | PARP1HPGDGAANFKB1NFKB2 | |
| SCHEMBL27030553 | 0.82 | PARP1 (0.62) | PARP1HPGDGAANFKB1NFKB2 | |
| SCHEMBL514262 | 0.82 | PARP1 (0.57) | PARP1HPGDGAANFKB1NFKB2 | |
| SCHEMBL145700 | 0.82 | KDM4E (0.59) | PARP1HPGDGAANFKB1NFKB2 | |
| SCHEMBL5488350 | 0.80 | SMN1; SMN2 (0.61) | PARP1HPGDGAANFKB1NFKB2 | |
| SCHEMBL28152817 | 0.80 | PTPN1 (0.65) | PARP1HPGDGAANFKB1NFKB2 | |
| SCHEMBL245137 | 0.79 | KDM4E (0.65) | SMN1; SMN2MAPK1KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023236426-A1 | AUTOMATIC CONTINUOUS FLOW SEMI-SYNTHESIS METHOD FOR VINCAMINE | 威胜生物医药(苏州)股份有限公司 | 2023-12-14 | — | — | WO | claimed |
| CN-114702494-A | Automatic continuous-flow semisynthesis method for vincamine | 张家港威胜生物医药有限公司 | 2022-07-05 | — | — | CN | claimed |
| WO-2023236426-A1 | AUTOMATIC CONTINUOUS FLOW SEMI-SYNTHESIS METHOD FOR VINCAMINE | 威胜生物医药(苏州)股份有限公司 | 2023-12-14 | — | — | WO | disclosed |
| CN-114702494-B | Automatic continuous flow semisynthesis method of vincamine | 张家港威胜生物医药有限公司 | 2022-09-27 | — | — | CN | disclosed |
| CN-114702494-A | Automatic continuous-flow semisynthesis method for vincamine | 张家港威胜生物医药有限公司 | 2022-07-05 | — | — | CN | disclosed |
| EP-2588502-B1 | POLYMERIZATION PROCESS WITH IN-SITU INITIATOR FORMATION | NOURYON CHEMICALS INT BV (NL) | 2021-03-31 | — | — | EP | disclosed |
| US-10280270-B2 | Silane functionalized polyolefins for polyolefin nanocomposites | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2019-05-07 | — | — | US | disclosed |
| US-20160145361-A1 | Silane Functionalized Polyolefins for Polyolefin Nanocomposites | EXXONMOBIL CHEMICAL PATENTS INC. | 2016-05-26 | — | — | US | disclosed |
| US-8987391-B2 | Polymerization process with in-situ initiator formation | AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) | 2015-03-24 | — | — | US | disclosed |
| CN-102958947-B | Polymerization process with in-situ initiator formation | AKZO NOBEL CHEMICALS INT BV | 2014-11-26 | — | — | CN | disclosed |
| US-20130211019-A1 | Polymerization Process with In-Situ Initiator Formation | AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) | 2013-08-15 | — | — | US | disclosed |
| US-5274015-A | And a polyarylene sulfide polymer | PHILLIPS PETROLEUM COMPANY (US) | 1993-12-28 | — | — | US | disclosed |
| US-5268450-A | Reating sodium hydrosulfide with a sulfur containing hydroxyphenylbenztriazole | PHILLIPS PETROLEUM COMPANY (US) | 1993-12-07 | — | — | US | disclosed |
| EP-0322639-B1 | (22R,23R,24S)-22,23-EPOXY-2 ALPHA, 3 ALPHA-ISOPROPYLIDENEDIOXY-B-HOMO-7-OXA-5 ALPHA-STIGMASTAN-6-ONE, PROCESS FOR PREPARATION THEREOF AND PLANT GROWTH REGULATING COMPOSITION CONTAINING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-05-20 | — | — | EP | disclosed |
| US-5013821-A | Biodegradable, dispensers for drug delivery | PHARMACEUTICAL DELIVERY SYSTEMS, INC. (US) | 1991-05-07 | — | — | US | disclosed |
| US-4959093-A | STEROID, BRASSINOLIDE DERIVATIVE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-09-25 | — | — | US | disclosed |
| US-4215043-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-07-29 | — | — | US | disclosed |
| US-4008175-A | Organic acid anhydride-peroxydicarbonate composition | PPG INDUSTRIES, INC. (US) | 1977-02-15 | — | — | US | disclosed |
| US-3985720-A | Polymerization of ethylenically unsaturated monomer employing a catalyst system comprising dialkylpyrocarbonate, organic acid anhydride, alkaline reagent and H2 O2 | PPG INDUSTRIES, INC. (US) | 1976-10-12 | — | — | US | disclosed |
| US-3978032-A | ALKALINE BUFFER, ANHYDRIDE, PERACID, ALKYL HALOFORMATE | PPG INDUSTRIES, INC. (US) | 1976-08-31 | — | — | US | disclosed |