Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR55 | Q9Y2T6 | 3/20 | 0.65 |
| ▸ | CNR1 | P21554 | 2/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.65 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | LIG1 | P18858 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13317135 | 0.89 | LMNA (0.53) | GPR55CNR1HTTGPR35CHRM2 | |
| SCHEMBL5479467 | 0.83 | CNR1 (0.63) | GPR55CNR1HTTGPR35CHRM2 | |
| SCHEMBL29443920 | 0.79 | GPR55 (1.00) | GPR55CNR1HTTGPR35CHRM2 | |
| SCHEMBL5485522 | 0.79 | GPR55 (0.68) | GPR55CNR1HTTGPR35CHRM2 | |
| SCHEMBL5479307 | 0.79 | GPR55 (0.68) | GPR55CNR1HTTGPR35CHRM2 | |
| SCHEMBL5478375 | 0.79 | GPR55 (1.00) | GPR55CNR1HTTGPR35CHRM2 | |
| SCHEMBL5474369 | 0.79 | GPR55 (0.68) | GPR55CNR1HTTGPR35CHRM2 | |
| SCHEMBL5480055 | 0.79 | GPR55 (0.68) | GPR55CNR1HTTGPR35CHRM2 | |
| SCHEMBL5484948 | 0.78 | HTT (0.52) | GPR55CNR1HTTGPR35CHRM2 | |
| SCHEMBL5482241 | 0.78 | CNR1 (0.55) | GPR55CNR1HTTGPR35CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070299102-A1 | Diphenyl Ox-Indol-2-One Compounds and Their Use in the Treatment of Cancer | TOPO TARGET A/S (DK) | 2007-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299102-A1 | Diphenyl Ox-Indol-2-One Compounds and Their Use in the Treatment of Cancer | MTOR, RICTOR, CDK4 | GPR55 2338/4885CNR1 973/4885HTT 1880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.