Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 3/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.38 |
| ▸ | ITGAV | P06756 | 2/20 | 0.38 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.38 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5487264 | 1.00 | CRHR1 (0.47) | CRHR1S1PR1KITNPC1RAB9A | |
| SCHEMBL5489508 | 0.98 | CRHR1 (0.49) | CRHR1S1PR1KITNPC1RAB9A | |
| SCHEMBL5490596 | 0.97 | CRHR1 (0.50) | CRHR1KITNPC1RAB9AMAPT | |
| SCHEMBL5487267 | 0.91 | CRHR1 (0.47) | CRHR1S1PR1KITNPC1RAB9A | |
| SCHEMBL5488464 | 0.91 | CRHR1 (0.47) | CRHR1S1PR1KITNPC1RAB9A | |
| SCHEMBL5489512 | 0.88 | CRHR1 (0.49) | CRHR1KITNPC1RAB9AMAPT | |
| SCHEMBL4541431 | 0.88 | MAPT (0.41) | CRHR1NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL4552137 | 0.88 | KCNQ3 (0.46) | CRHR1NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL5490598 | 0.87 | CRHR1 (0.50) | CRHR1KITNPC1RAB9AMAPT | |
| SCHEMBL4552349 | 0.87 | MAPT (0.40) | CRHR1NPC1RAB9AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |