Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 3/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.42 |
| ▸ | SMO | Q99835 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 2/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | TEK | Q02763 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5487267 | 1.00 | CRHR1 (0.47) | CRHR1MAPK14SMOKITS1PR1 | |
| SCHEMBL5489512 | 0.98 | CRHR1 (0.49) | CRHR1MAPK14SMOKITNPC1 | |
| SCHEMBL5490598 | 0.97 | CRHR1 (0.50) | CRHR1MAPK14SMOKITNPC1 | |
| SCHEMBL4551651 | 0.94 | CRHR1 (0.45) | CRHR1MAPK14SMONPC1RAB9A | |
| SCHEMBL14534670 | 0.94 | MAPK14 (0.46) | CRHR1MAPK14 | |
| SCHEMBL5490935 | 0.93 | CRHR1 (0.45) | CRHR1MAPK14SMOLCKKDR | |
| SCHEMBL5488461 | 0.91 | CRHR1 (0.47) | CRHR1MAPK14KITS1PR1NPC1 | |
| SCHEMBL5487264 | 0.91 | CRHR1 (0.47) | CRHR1MAPK14KITS1PR1NPC1 | |
| SCHEMBL4408418 | 0.90 | CRHR1 (0.48) | CRHR1MAPK14 | |
| SCHEMBL5487361 | 0.89 | MAPK14 (0.47) | CRHR1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |