Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL277286 | 0.88 | CYP2C9 (0.54) | CYP2C9CYP2C19CA12CA1CA2 | |
| SCHEMBL845538 | 0.82 | CYP2C9 (0.51) | CYP2C9CYP2C19CA12CA1CA2 | |
| SCHEMBL5481626 | 0.82 | CYP2C9 (0.59) | CYP2C9CYP2C19CA12CA1CA2 | |
| SCHEMBL28585768 | 0.79 | CYP2C19 (0.69) | CYP2C9CYP2C19CA12CA1CA2 | |
| SCHEMBL29382818 | 0.79 | CYP2C19 (0.69) | CYP2C9CYP2C19CA12CA1CA2 | |
| SCHEMBL29877603 | 0.79 | ALDH1A1 (0.47) | CYP2C9CYP2C19CA12CA1CA2 | |
| SCHEMBL4726039 | 0.79 | ALDH1A1 (0.47) | CYP2C9CYP2C19CA12CA1CA2 | |
| SCHEMBL20719679 | 0.79 | DPP4 (0.51) | CYP2C9CYP2C19KDM4EALDH1A1MAPK1 | |
| SCHEMBL29156396 | 0.78 | MAPT (0.45) | KDM4EMAOBALDH1A1HSD17B10TSHR | |
| SCHEMBL30684644 | 0.78 | MAPT (0.45) | KDM4EMAOBALDH1A1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |