Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29156396 | 1.00 | MAPT (0.45) | MAPTSMN1; SMN2LMNAPOLBALDH1A1 | |
| SCHEMBL10465583 | 0.90 | ALDH1A1 (0.52) | MAPTSMN1; SMN2LMNAPOLBALDH1A1 | |
| SCHEMBL2199853 | 0.80 | CA12 (0.51) | MAPTSMN1; SMN2LMNAPOLBALDH1A1 | |
| SCHEMBL9103181 | 0.79 | MAPT (0.50) | MAPTSMN1; SMN2LMNAPOLBALDH1A1 | |
| SCHEMBL2202907 | 0.79 | MAOB (0.50) | MAPTSMN1; SMN2LMNAPOLBALDH1A1 | |
| SCHEMBL6421455 | 0.78 | MAPT (0.55) | MAPTSMN1; SMN2ALDH1A1KDM4ERXFP1 | |
| SCHEMBL5488554 | 0.78 | CYP2C9 (0.47) | ALDH1A1KDM4ETSHRHSD17B10MAOB | |
| SCHEMBL2199970 | 0.78 | PDGFRB (0.52) | MAPTSMN1; SMN2LMNAPOLBALDH1A1 | |
| SCHEMBL16620896 | 0.75 | MAPT (0.46) | MAPTSMN1; SMN2LMNAPOLBALDH1A1 | |
| SCHEMBL8911265 | 0.74 | ALDH1A1 (0.53) | MAPTSMN1; SMN2LMNAPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110278711-B | Tricyclosulfones as rory modulators | 百时美施贵宝公司 | 2023-12-15 | — | — | CN | disclosed |