SCHEMBL5488608

SCHEMBL5488608

C=C(C(N)=O)c1cccc(Br)c1Br

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PRNP P04156 1/20 0.35
METAP2 P50579 1/20 0.34
PARP1 P09874 1/20 0.33
MAOB P27338 1/20 0.33
MIF P14174 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ALDH1A1 P00352 3/20 0.33
LMNA P02545 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
HPGD P15428 2/20 0.32
HSD17B10 Q99714 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MAPT P10636 1/20 0.32
TSHR P16473 1/20 0.32
FABP4 P15090 1/20 0.32
GAA P10253 1/20 0.31
SLC9A1 P19634 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31162480 0.84 NPC1 (0.42) METAP2MIFMEN1KMT2AALDH1A1
SCHEMBL5495519 0.82 ERN1 (0.37)
SCHEMBL372707 0.82 PRNP (0.40) PRNPMAOBMEN1KMT2AALDH1A1
SCHEMBL3170417 0.79 METAP2 (0.48) METAP2PARP1ALDH1A1HPGDHSD17B10
SCHEMBL8495468 0.74 PRNP (0.50) PRNPMAOBMEN1KMT2AALDH1A1
SCHEMBL588389 0.73 PRNP (0.53) PRNPKMT2AALDH1A1LMNAHPGD
SCHEMBL9136350 0.71 PRNP (0.56) PRNPMAOBMEN1KMT2AALDH1A1
SCHEMBL11695884 0.71 GAA (0.40) PRNPMAOBMIFMEN1KMT2A
SCHEMBL28482995 0.71 PRNP (0.39) PRNPMAOBMEN1KMT2AALDH1A1
SCHEMBL1873518 0.71 KMT2A (0.41) PRNPMEN1KMT2AALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070042275-A1 Composition for optical recording, optical recording medium, and production method thereof FUJI PHOTO FILM CO., LTD. 2007-02-22 US disclosed