Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 2/20 | 0.49 |
| ▸ | TACR1 | P25103 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NMBR | P28336 | 5/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4614285 | 0.87 | NMBR (0.52) | PIN1TACR1HDAC3HDAC4HDAC1 | |
| SCHEMBL5496357 | 0.83 | PIN1 (0.43) | PIN1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL18725627 | 0.82 | KMT2A (0.55) | KMT2A | |
| SCHEMBL18826572 | 0.82 | KMT2A (0.48) | KMT2A | |
| SCHEMBL17935596 | 0.82 | KMT2A (0.55) | KMT2A | |
| SCHEMBL4890850 | 0.81 | TACR1 (0.53) | TACR1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4890847 | 0.81 | TACR1 (0.53) | TACR1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL21461837 | 0.80 | KMT2A (0.55) | KMT2A | |
| SCHEMBL29400817 | 0.80 | KMT2A (0.53) | KMT2A | |
| SCHEMBL2947901 | 0.80 | KMT2A (0.53) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7163921-B1 | Peptide derivatives and medicinal compositions | NIPPON SHINYAKU CO., LTD. (JP) | 2007-01-16 | — | — | US | disclosed |
| EP-1275657-A1 | PEPTIDE DERIVATIVES AND MEDICINAL COMPOSITIONS | Nippon Shinyaku Co., Ltd. (JP) | 2003-01-15 | — | — | EP | disclosed |