Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.31 |
| ▸ | ITGA2 | P17301 | 2/20 | 0.31 |
| ▸ | F2R | P25116 | 3/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL1731718 | 0.85 | THRA (0.37) | ITGB3ITGA2BITGA2F2R | |
| Trifluoroacetic Acid SCHEMBL1729711 | 0.85 | ITGB3 (0.32) | ITGB3ITGA2BITGA2F2R | |
| Bromide SCHEMBL1732551 | 0.83 | F2R (0.36) | F2RFFAR4 | |
| Bromide SCHEMBL1731216 | 0.82 | F2R (0.37) | F2R | |
| Bromide SCHEMBL1730546 | 0.81 | F2R (0.38) | F2R | |
| Bromide SCHEMBL5491800 | 0.81 | F2R (0.38) | F2R | |
| Bromide SCHEMBL1732270 | 0.81 | F2R (0.36) | F2R | |
| Trifluoroacetic Acid SCHEMBL5490918 | 0.81 | F2R (0.44) | F2R | |
| Bromide SCHEMBL1730045 | 0.81 | F2R (0.32) | F2R | |
| Bromide SCHEMBL1730158 | 0.80 | F2R (0.37) | F2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7244730-B2 | 2-iminopyrrolidine derivatives | EISAI CO., LTD (JP) | 2007-07-17 | — | — | US | disclosed |
| US-20050245592-A1 | 2-Iminopyrrolidine derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2005-11-03 | — | — | US | disclosed |
| US-20050004204-A1 | 2-Iminopyrrolidine derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2005-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050245592-A1 | 2-Iminopyrrolidine derivatives | H1-2, H1-3, H1-0 | ITGB3 3634/4885ITGA2B 4046/4885ITGA2 3420/4885 |
| US-20050004204-A1 | 2-Iminopyrrolidine derivatives | H1-2, H1-3, H1-0 | ITGB3 3648/4885ITGA2B 4058/4885ITGA2 3435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.