Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 3/20 | 0.59 |
| ▸ | MAOA | P21397 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | ACHE | P22303 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.44 |
| ▸ | CDK9 | P50750 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4235603 | 0.79 | CYP3A4 (0.59) | CYP2A6MAOACYP3A4HSD17B10ACHE | |
| SCHEMBL7830030 | 0.79 | CYP2A6 (0.59) | CYP2A6MAOACYP3A4HSD17B10ACHE | |
| SCHEMBL3467047 | 0.79 | CYP3A4 (0.59) | CYP2A6MAOACYP3A4HSD17B10ACHE | |
| SCHEMBL4247907 | 0.79 | MAOA (0.54) | CYP2A6MAOACYP3A4HSD17B10ACHE | |
| SCHEMBL4419431 | 0.78 | CYP2A6 (0.56) | CYP2A6MAOACYP3A4HSD17B10ACHE | |
| SCHEMBL8936325 | 0.77 | MAOA (0.56) | CYP2A6MAOACYP3A4HSD17B10ACHE | |
| SCHEMBL7003510 | 0.76 | MAOA (0.54) | CYP2A6MAOACYP3A4HSD17B10ACHE | |
| SCHEMBL1301705 | 0.76 | CYP3A4 (0.62) | CYP2A6MAOACYP3A4HSD17B10ACHE | |
| SCHEMBL6991403 | 0.76 | MAOA (0.54) | CYP2A6MAOACYP3A4HSD17B10ACHE | |
| SCHEMBL6995029 | 0.76 | MAOA (0.54) | CYP2A6MAOACYP3A4HSD17B10ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107298686-B | A kind of psoralen amine derivant and purposes | 中国科学院新疆理化技术研究所 | 2018-10-26 | — | — | CN | claimed |
| CN-107298686-A | A kind of psoralen amine derivant and purposes | 中国科学院新疆理化技术研究所 | 2017-10-27 | — | — | CN | claimed |
| CN-1248178-A | Method and device for reducing small organic molecules in blood products | CERUS CORP (US) | 2000-03-22 | — | — | CN | claimed |
| US-5473083-A | Skin disorders, cancer, Aids | LEHIGH UNIVERSITY (US) | 1995-12-05 | — | — | US | claimed |
| CN-107814809-B | A kind of psoralen derivative and purposes of the triazole containing phenyl | 中国科学院新疆理化技术研究所 | 2019-07-19 | — | — | CN | disclosed |
| CN-107298686-B | A kind of psoralen amine derivant and purposes | 中国科学院新疆理化技术研究所 | 2018-10-26 | — | — | CN | disclosed |
| CN-107298686-B | A kind of psoralen amine derivant and purposes | 中国科学院新疆理化技术研究所 | 2018-10-26 | — | — | CN | disclosed |
| CN-107298686-B | A kind of psoralen amine derivant and purposes | 中国科学院新疆理化技术研究所 | 2018-10-26 | — | — | CN | disclosed |
| CN-107814809-A | The psoralen derivative and purposes of a kind of triazole containing phenyl | 中国科学院新疆理化技术研究所 | 2018-03-20 | — | — | CN | disclosed |
| CN-107298686-A | A kind of psoralen amine derivant and purposes | 中国科学院新疆理化技术研究所 | 2017-10-27 | — | — | CN | disclosed |
| CN-107298686-A | A kind of psoralen amine derivant and purposes | 中国科学院新疆理化技术研究所 | 2017-10-27 | — | — | CN | disclosed |
| CN-107298686-A | A kind of psoralen amine derivant and purposes | 中国科学院新疆理化技术研究所 | 2017-10-27 | — | — | CN | disclosed |
| US-20050153913-A1 | Nucleic acid carrier compositions and methods for their synthesis | KOSAK KENNETH M (US) | 2005-07-14 | — | — | US | disclosed |
| CN-1136042-C | Flow device for the reduction of compounds from biological compositions and methods of use | 3 | 2004-01-28 | — | — | CN | disclosed |
| CN-1132676-C | Method and device for reducing small organic molecules in blood products | CERUS CORP. (US) | 2003-12-31 | — | — | CN | disclosed |
| CN-1284896-A | Flow device for the reduction of compounds from biological compositions and methods of use | CERUS CORP (US) | 2001-02-21 | — | — | CN | disclosed |
| CN-1284897-A | Batch devices for reduction of compounds from biological compositions containing cells and methods of use | CERUS CORP (US) | 2001-02-21 | — | — | CN | disclosed |
| CN-1248178-A | Method and device for reducing small organic molecules in blood products | CERUS CORP (US) | 2000-03-22 | — | — | CN | disclosed |
| US-5473083-A | Skin disorders, cancer, Aids | LEHIGH UNIVERSITY (US) | 1995-12-05 | — | — | US | disclosed |
| US-5356929-A | Skin, blood and bone marrow disorders | LEHIGH UNIVERSITY (US) | 1994-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050153913-A1 | Nucleic acid carrier compositions and methods for their synthesis | DNA2, POLRMT, SLC29A2 | CYP2A6 1547/4885MAOA 3441/4885CYP3A4 3796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.