Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 2/20 | 0.75 |
| ▸ | MET | P08581 | 13/20 | 0.69 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.53 |
| ▸ | ATR | Q13535 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30453716 | 0.85 | CSF1R (1.00) | CSF1RMETALKATRHRH3 | |
| SCHEMBL487740 | 0.85 | CSF1R (1.00) | CSF1RMETALKATRHRH3 | |
| SCHEMBL5488534 | 0.85 | CSF1R (1.00) | CSF1RMETALKATRHRH3 | |
| SCHEMBL487623 | 0.81 | MET (1.00) | CSF1RMETALKATR | |
| SCHEMBL487952 | 0.81 | MET (1.00) | CSF1RMETALKATR | |
| SCHEMBL489386 | 0.81 | MET (1.00) | CSF1RMETALKATR | |
| SCHEMBL30452772 | 0.81 | MET (1.00) | CSF1RMETALKATR | |
| SCHEMBL30453496 | 0.81 | MET (1.00) | CSF1RMETALKATR | |
| SCHEMBL488321 | 0.77 | MET (1.00) | CSF1RMETALK | |
| SCHEMBL6417569 | 0.77 | MET (1.00) | CSF1RMETALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070072874-A1 | Aminoheteroaryl compounds as protein kinase inhibitors | SUGEN, INC. | 2007-03-29 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070072874-A1 | Aminoheteroaryl compounds as protein kinase inhibitors | MET, MAP4K1, MAP4K2 | CSF1R 757/4885MET 1/4885ALK 138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.