Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29029671 | 0.81 | TSHR (0.41) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL29073795 | 0.81 | TSHR (0.40) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL18166514 | 0.80 | TSHR (0.37) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL29407615 | 0.79 | ALDH1A1 (0.42) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL27444642 | 0.79 | TSHR (0.39) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL1070261 | 0.79 | TSHR (0.39) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL1898814 | 0.79 | TSHR (0.39) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL19495089 | 0.79 | TSHR (0.36) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL302801 | 0.78 | THRB (0.43) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL9578343 | 0.78 | TSHR (0.38) | TSHRHPGDTHRBALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217769-B2 | Medical device with plasma cross-linked hydrophilic coating | BIOSURFACE ENGINEERING TECHNOLOGIES, INC. (US) | 2007-05-15 | — | — | US | disclosed |
| US-20040258931-A1 | Medical device with plasma cross-linked hydrophilic coating | BIOSURFACE ENGINEERING TECHNOLOGIES, INC. | 2004-12-23 | — | — | US | disclosed |
| US-6765069-B2 | FORMED FROM N-TRIMETHYLSILYL-ALLYLAMINE, ETHYLENE, PROPYLENE AND ALLYL ALCOHOL; FOR USE ON MEDICAL EQUIPMENT, COSMETICS | BIOSURFACE ENGINEERING TECHNOLOGIES, INC. | 2004-07-20 | — | — | US | disclosed |
| US-20030091827-A1 | Plasma cross-linked hydrophilic coating | BIOSURFACE ENGINEERING TECHNOLOGIES, INC. | 2003-05-15 | — | — | US | disclosed |
| WO-2003027152-A1 | PLASMA CROSS-LINKED HYDROPHILIC COATING | BIOSURFACE ENGINEERING TECHNOLOGIES, INC. (US) | 2003-04-03 | — | — | WO | disclosed |
| US-5871823-A | ACTIVATION OF POLYMER WITH ULTRAVIOLET LIGHT IN THE PRESENCE OF OXYGEN, IMMERSION AND GRAFT POLYMERIZATION WITH VINYL MONOMER | HUELS AKTIENGESELLSCHAFT (DE) | 1999-02-16 | — | — | US | disclosed |