Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6989374 | 0.78 | PARP1 (0.50) | L3MBTL1PARP1CYP2C19F10MEN1 | |
| SCHEMBL31719066 | 0.72 | HTR2A (0.44) | HTR2ACYP2C19HTR2CMEN1KMT2A | |
| SCHEMBL23582699 | 0.72 | CYP4F2 (0.69) | PARP1ALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL26144962 | 0.72 | SRD5A2 (0.59) | ALDH1A1KDM2BKDM4ESRD5A2PDK2 | |
| SCHEMBL3673373 | 0.71 | AKR1B1 (0.47) | HTR2ACYP2C19HTR2CKMT2A | |
| SCHEMBL16409435 | 0.70 | KDM2B (0.69) | L3MBTL1PARP1ALDH1A1KDM2BMEN1 | |
| SCHEMBL31375622 | 0.70 | KDM2B (0.69) | L3MBTL1PARP1ALDH1A1KDM2BMEN1 | |
| SCHEMBL23579339 | 0.70 | HSD11B1 (0.58) | PARP1ALDH1A1CYP2C19KDM2BSMN1; SMN2 | |
| SCHEMBL29973506 | 0.70 | HSD11B1 (0.58) | PARP1ALDH1A1CYP2C19KDM2BSMN1; SMN2 | |
| SCHEMBL14067799 | 0.70 | NPSR1 (0.49) | L3MBTL1ALDH1A1KDM2BSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856031-A1 | 2-ARYLPROPIONIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DOMPE' pha.r.ma s.p.a. (IT) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006063999-A1 | 2-ARYLPROPIONIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DOMPE' PHA.R.MA.S.P.A. (IT) | 2006-06-22 | — | — | WO | disclosed |