Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 7/20 | 0.50 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.44 |
| ▸ | IDH1 | O75874 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 3/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11119221 | 0.87 | KEAP1 (0.57) | PARP1MEP1BFOLH1TSHRPOLB | |
| SCHEMBL1405064 | 0.86 | ALDH1A1 (0.56) | PARP1MEP1BMEN1KMT2AFOLH1 | |
| SCHEMBL8415332 | 0.84 | L3MBTL1 (0.47) | PARP1MEP1BMEN1KMT2AFOLH1 | |
| SCHEMBL10189495 | 0.83 | PARP1 (0.56) | PARP1MEP1BFOLH1KDM1AMAOA | |
| SCHEMBL3054119 | 0.83 | CYP4F2 (0.62) | PARP1MEP1BFOLH1IDH1F10 | |
| SCHEMBL8342426 | 0.83 | TAAR1 (0.55) | PARP1MEP1BFOLH1 | |
| SCHEMBL23582699 | 0.82 | CYP4F2 (0.69) | PARP1MEN1KMT2AFOLH1CYP4F2 | |
| SCHEMBL5232156 | 0.81 | PARP1 (0.53) | PARP1MEP1BFOLH1IDH1F10 | |
| SCHEMBL5645749 | 0.81 | PARP1 (0.53) | PARP1MEP1BFOLH1IDH1F10 | |
| Hydrochloric Acid SCHEMBL28744996 | 0.81 | TAAR1 (0.53) | PARP1MEP1BFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341755-A1 | CARBOXYLIC ACID AMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF THROMBOEMBOLIC DISEASES AND TUMOURS | MERCK PATENT GmbH (DE) | 2003-09-10 | — | — | EP | claimed |
| WO-2002048099-A1 | CARBOXYLIC ACID AMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF THROMBOEMBOLIC DISEASES AND TUMOURS | MERCK PATENT GMBH (DE) | 2002-06-20 | — | — | WO | claimed |