Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | PRCP | P42785 | 2/20 | 0.37 |
| ▸ | CTSC | P53634 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 2/20 | 0.33 |
| ▸ | SCN4A | P35499 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5489340 | 1.00 | DPP7 (0.41) | DPP7PRCPCTSCCYP3A4CYP2D6 | |
| SCHEMBL5494046 | 0.88 | DPP7 (0.44) | DPP7PRCPCTSCCYP3A4CYP2D6 | |
| SCHEMBL5494049 | 0.88 | DPP7 (0.44) | DPP7PRCPCTSCCYP3A4CYP2D6 | |
| SCHEMBL5495019 | 0.80 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL5495013 | 0.80 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL16853543 | 0.80 | DPP7 (0.49) | DPP7PRCPCTSCCYP3A4CYP2D6 | |
| SCHEMBL30729269 | 0.79 | DPP7 (0.48) | DPP7PRCPCTSCCYP3A4CYP2D6 | |
| SCHEMBL10537153 | 0.79 | DPP7 (0.48) | DPP7PRCPCTSCCYP3A4CYP2D6 | |
| SCHEMBL30729221 | 0.79 | DPP7 (0.48) | DPP7PRCPCTSCCYP3A4CYP2D6 | |
| SCHEMBL6401404 | 0.79 | DPP7 (0.48) | DPP7PRCPCTSCCYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166579-B2 | Prodrugs of DP IV-inhibitors | PROSIDION LIMITED (GB) | 2007-01-23 | — | — | US | claimed |