Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
| ▸ | PRCP | P42785 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | CTSC | P53634 | 3/20 | 0.36 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 2/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5494049 | 1.00 | DPP7 (0.44) | DPP7PRCPHDAC3HDAC4HDAC1 | |
| SCHEMBL5489331 | 0.88 | DPP7 (0.41) | DPP7PRCPCTSCTLR2CYP1A2 | |
| SCHEMBL5489340 | 0.88 | DPP7 (0.41) | DPP7PRCPCTSCTLR2CYP1A2 | |
| SCHEMBL5489377 | 0.82 | ACACB (0.34) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL5489371 | 0.82 | ACACB (0.34) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL24766527 | 0.81 | L3MBTL1 (0.51) | DPP7PRCPHDAC3HDAC4HDAC1 | |
| SCHEMBL8720606 | 0.81 | L3MBTL1 (0.51) | DPP7PRCPHDAC3HDAC4HDAC1 | |
| SCHEMBL30729237 | 0.81 | L3MBTL1 (0.51) | DPP7PRCPHDAC3HDAC4HDAC1 | |
| SCHEMBL16899848 | 0.81 | L3MBTL1 (0.51) | DPP7PRCPHDAC3HDAC4HDAC1 | |
| SCHEMBL8720605 | 0.81 | L3MBTL1 (0.51) | DPP7PRCPHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166579-B2 | Prodrugs of DP IV-inhibitors | PROSIDION LIMITED (GB) | 2007-01-23 | — | — | US | claimed |