Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | DDOST | P39656 | 1/20 | 0.33 |
| ▸ | TRHR | P34981 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5495013 | 1.00 | SMN1; SMN2 (0.35) | SMN1; SMN2POLBMEN1KMT2AACACB | |
| SCHEMBL5489371 | 0.89 | ACACB (0.34) | SMN1; SMN2POLBMEN1KMT2AACACB | |
| SCHEMBL5489377 | 0.89 | ACACB (0.34) | SMN1; SMN2POLBMEN1KMT2AACACB | |
| SCHEMBL5489331 | 0.80 | DPP7 (0.41) | — | |
| SCHEMBL5489340 | 0.80 | DPP7 (0.41) | — | |
| SCHEMBL25834354 | 0.79 | POLB (0.42) | SMN1; SMN2POLBMEN1KMT2AACACB | |
| SCHEMBL14943195 | 0.79 | POLB (0.42) | SMN1; SMN2POLBMEN1KMT2AACACB | |
| SCHEMBL2597780 | 0.78 | SMN1; SMN2 (0.42) | SMN1; SMN2POLBMEN1KMT2AACACB | |
| SCHEMBL20560032 | 0.78 | SMN1; SMN2 (0.42) | SMN1; SMN2POLBMEN1KMT2AACACB | |
| SCHEMBL2597779 | 0.78 | SMN1; SMN2 (0.42) | SMN1; SMN2POLBMEN1KMT2AACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166579-B2 | Prodrugs of DP IV-inhibitors | PROSIDION LIMITED (GB) | 2007-01-23 | — | — | US | claimed |