Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTBP2 | P56545 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | GPR52 | Q9Y2T5 | 3/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL678767 | 1.00 | CTBP2 (0.45) | CTBP2TAAR1GAAKMT2AAKR1C3 | |
| SCHEMBL1137147 | 0.83 | AKR1B1 (0.47) | TAAR1AKR1C3GPR52TBXAS1 | |
| SCHEMBL1060627 | 0.83 | AKR1B1 (0.47) | TAAR1AKR1C3GPR52TBXAS1 | |
| SCHEMBL19656187 | 0.83 | GPR52 (0.55) | TAAR1KMT2AAKR1C3ALDH1A1GPR52 | |
| SCHEMBL11395760 | 0.83 | CTBP2 (0.47) | CTBP2GAAKMT2AAKR1C3PPARG | |
| SCHEMBL5489366 | 0.83 | CTBP2 (0.47) | CTBP2GAAKMT2AAKR1C3PPARG | |
| SCHEMBL1920921 | 0.82 | CTBP2 (0.44) | CTBP2TAAR1AKR1C3MAOB | |
| SCHEMBL440569 | 0.82 | CTBP2 (0.44) | CTBP2TAAR1AKR1C3MAOB | |
| SCHEMBL3681656 | 0.80 | TDP1 (0.50) | KMT2AKDM4E | |
| SCHEMBL1624072 | 0.80 | MTNR1A (0.54) | TAAR1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121802-B1 | HIGH REFRACTIVE INDEX SILOXANE INSERT MATERIALS FOR EMBEDDED CONTACT LENSES | ALCON INC (CH) | 2024-07-17 | — | — | EP | claimed |
| EP-3728339-B1 | COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS | AMO Ireland (IE) | 2022-07-06 | — | — | EP | claimed |
| EP-2268709-B1 | SCRATCH RESISTANT THERMOPLASTIC RESIN COMPOSITION | CHEIL IND INC (KR) | 2013-10-02 | — | — | EP | claimed |
| EP-2204412-B1 | Polycarbonate resin composition with improved scratch resistance and melt flow index | CHEIL IND INC (KR) | 2012-08-29 | — | — | EP | claimed |
| EP-3728339-B1 | COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS | AMO Ireland (IE) | 2022-07-06 | — | — | EP | disclosed |
| EP-3728339-A1 | COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS | Merck Patent GmbH (DE) | 2020-10-28 | — | — | EP | disclosed |
| EP-3502147-A1 | COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS | Merck Patent GmbH (DE) | 2019-06-26 | — | — | EP | disclosed |