SCHEMBL5489382

SCHEMBL5489382

Cc1c[c]cc(I)c1O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL320244 0.83
SCHEMBL1276510 0.76
SCHEMBL28235112 0.72
SCHEMBL6308990 0.72
SCHEMBL6196771 0.72 APP (0.38)
SCHEMBL17435131 0.71
SCHEMBL486898 0.69 CYP2C9 (0.48)
SCHEMBL27863649 0.69 GABRA1 (0.39)
SCHEMBL5468861 0.67 KDM4E (0.50)
SCHEMBL27712554 0.67 LMNA (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1783221-A1 Production of adenine nucleotide translocator (ANT), novel ANT ligands and screening assays therefor MIGENIX Corp. (US) 2007-05-09 EP disclosed
US-7001729-B2 Production of adenine nucleotide translocator (ANT), novel ANT ligands and screening assays therefor MIGENIX CORP. (US) 2006-02-21 US disclosed
US-6906174-B2 Production of adenine nucleotide translocator (ANT), novel ANT ligands and screening assays therefor MIGENIX CORP. (US) 2005-06-14 US disclosed
US-6906175-B2 Production of adenine nucleotide translocator (ANT), novel ANT ligands and screening assays therefor. MIGENIX CORP. (US) 2005-06-14 US disclosed
US-6902908-B2 Production of adenine nucleotide translocator (ANT), novel ANT ligands and screening assays therefor MIGENIX CORP. (US) 2005-06-07 US disclosed
US-6887670-B2 Production of adenine nucleotide translocator (ANT), novel ANT ligands and screening assays therefor MIGENIX CORP. (US) 2005-05-03 US disclosed
US-20050064530-A1 PRODUCTION OF ADENINE NUCLEOTIDE TRANSLOCATOR (ANT), NOVEL ANT LIGANDS AND SCREENING ASSAYS THEREFOR MIGENIX CORP. 2005-03-24 US disclosed
US-20050019835-A1 PRODUCTION OF ADENINE NUCLEOTIDE TRANSLOCATOR (ANT), NOVEL ANT LIGANDS AND SCREENING ASSAYS THEREFOR MIGENIX CORP. 2005-01-27 US disclosed
US-20050003353-A1 PRODUCTION OF ADENINE NUCLEOTIDE TRANSLOCATOR (ANT), NOVEL ANT LIGANDS AND SCREENING ASSAYS THEREFOR MIGENIX CORP. 2005-01-06 US disclosed
US-20050003352-A1 PRODUCTION OF ADENINE NUCLEOTIDE TRANSLOCATOR (ANT), NOVEL ANT LIGANDS AND SCREENING ASSAYS THEREFOR MIGENIX CORP. 2005-01-06 US disclosed
US-20040241801-A1 Production of adenine nucleotide translocator (ANT), novel ANT ligands and screening assays therefor MITOKOR, INC. 2004-12-02 US disclosed
EP-1283884-A2 PRODUCTION OF ADENINE NUCLEOTIDE TRANSLOCATOR (ANT), NOVEL ANT LIGANDS AND SCREENING ASSAYS THEREFOR MITOKOR (US) 2003-02-19 EP disclosed
US-20020012992-A1 Production of adenine nucleotide translocator (ANT), novel ANT ligands and screening assays therefor MIGENIX CORP. 2002-01-31 US disclosed
US-20010044144-A1 Production of adenine nucleotide translocator (ANT), novel ANT ligands and screening assays therefor MIGENIX CORP. 2001-11-22 US disclosed
WO-2001085944-A2 PRODUCTION OF ADENINE NUCLEOTIDE TRANSLOCATOR (ANT), NOVEL ANT LIGANDS AND SCREENING ASSAYS THEREFOR MITOKOR (US) 2001-11-15 WO disclosed
WO-2000026370-A9 ADENINE NUCLEOTIDE TRANSLOCATOR (ANT) FUSION PROTEINS AND USES THEREOF MITOKOR (US) 2001-11-15 WO disclosed
EP-1049780-A1 ADENINE NUCLEOTIDE TRANSLOCATOR (ANT) FUSION PROTEINS AND USES THEREOF MITOKOR (US) 2000-11-08 EP disclosed
WO-2000026370-A2 ADENINE NUCLEOTIDE TRANSLOCATOR (ANT) FUSION PROTEINS AND USES THEREOF MITOKOR (US) 2000-05-11 WO disclosed