Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | RRM1 | P23921 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | MITF | O75030 | 2/20 | 0.50 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.49 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.49 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.49 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.49 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.49 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5489426 | 1.00 | IKBKB (0.60) | IKBKBALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL5484233 | 0.92 | MEN1 (0.53) | IKBKBALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL5484229 | 0.92 | MEN1 (0.53) | IKBKBALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL5487804 | 0.89 | GPR27 (0.54) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL5489322 | 0.89 | GPR27 (0.60) | IKBKBALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL5487810 | 0.89 | GPR27 (0.54) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL5489320 | 0.89 | GPR27 (0.60) | IKBKBALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL5487532 | 0.85 | KMT2A (0.62) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL5480579 | 0.85 | POLB (0.53) | IKBKBALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL5480578 | 0.85 | POLB (0.53) | IKBKBALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1845083-A2 | New arylsulfonohydrazide inhibitors of enzymes MurC and MurD | UNIVERZA V LJUBLJANI, FAKULTETA ZA FARMACIJO (SI) | 2007-10-17 | — | — | EP | disclosed |