Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | NPC1 | O15118 | 4/20 | 0.62 |
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | PLG | P00747 | 1/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.51 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | KAT6A | Q92794 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5487810 | 0.89 | GPR27 (0.54) | KMT2AMEN1NPC1RAB9AKAT6A | |
| SCHEMBL5489322 | 0.89 | GPR27 (0.60) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL5489320 | 0.89 | GPR27 (0.60) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL5487804 | 0.89 | GPR27 (0.54) | KMT2AMEN1NPC1RAB9AKAT6A | |
| SCHEMBL5489426 | 0.85 | IKBKB (0.60) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL5489429 | 0.85 | IKBKB (0.60) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL5482273 | 0.82 | GPR27 (0.48) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL5484233 | 0.81 | MEN1 (0.53) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL5484229 | 0.81 | MEN1 (0.53) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL5483664 | 0.79 | KAT6A (0.53) | KMT2AMEN1NPC1RAB9AKAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1845083-A2 | New arylsulfonohydrazide inhibitors of enzymes MurC and MurD | UNIVERZA V LJUBLJANI, FAKULTETA ZA FARMACIJO (SI) | 2007-10-17 | — | — | EP | disclosed |