SCHEMBL5489463

SCHEMBL5489463

C=CCC1(CC=C)CC(=O)NC1=O

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
MMP9 P14780 1/20 0.33
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32
CYP2C19 P33261 1/20 0.32
CYP19A1 P11511 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9490710 0.81 CRBN (0.37) TSHRNPSR1MMP9CYP19A1
SCHEMBL14378011 0.75 TSHR (0.39) TSHRNPSR1MMP9KDM4ELMNA
SCHEMBL3189534 0.74 TSHR (0.36) TSHRNPSR1MMP9KDM4ELMNA
SCHEMBL11037065 0.74 TSHR (0.36) TSHRNPSR1MMP9KDM4ELMNA
SCHEMBL22007695 0.73 CYP19A1 (0.41) MMP9CYP19A1
SCHEMBL4563653 0.73 MMP9 (0.33) MMP9
SCHEMBL3706662 0.71 TSHR (0.58) TSHRNPSR1KDM4ELMNACYP2C19
SCHEMBL11122418 0.71 TSHR (0.41) TSHRNPSR1KDM4ELMNACYP2C19
SCHEMBL10676973 0.71 KDM4E (0.39) TSHRNPSR1MMP9KDM4ELMNA
SCHEMBL10689939 0.70 ALDH1A1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115537254-A High-temperature-resistant wear-resistant engine lubricating oil composition and preparation method thereof 湖北金曼利石化有限公司 2022-12-30 CN claimed
CN-114133917-A Heat conduction oil composition with biodegradability and preparation method thereof 中国石油化工股份有限公司 2022-03-04 CN claimed
CN-112522013-A Additive for repairing wear scratches in automobile engine and preparation method thereof 辽宁汽众润滑油生产有限公司 2021-03-19 CN claimed
CN-109439290-B Environment-friendly organic heat carrier and preparation method thereof 山东恒利热载体工程技术有限公司 2021-03-16 CN disclosed
CN-112322351-A Hydrofining scale inhibitor and preparation method and application thereof 中国石油化工股份有限公司 2021-02-05 CN disclosed
CN-111040829-A Antiwear energy-saving agent, preparation method and application 贵州中时烯材科技有限公司 2020-04-21 CN disclosed
US-20190177651-A1 LUBRICANT COMPOSITIONS COMPRISING OLEFIN COPOLYMER DISPERSANTS IN COMBINATION WITH ADDITIVES AFTON CHEMICAL CORPORATION 2019-06-13 US disclosed
US-20160201001-A1 ADDITIVE FOR OIL-BASED LUBRICANTS HAVING IMPROVED EXTREME PRESSURE PROPERTIES Terralub GmbH (DE) 2016-07-14 US disclosed
CN-104004575-A Low-temperature-resistant 5W-40 type liquefied natural gas vehicle engine oil UNIV SHAANXI NORMAL 2014-08-27 CN disclosed
WO-2014003162-A1 LUBRICANT COMPOSITION 出光興産株式会社 (JP) 2014-01-03 WO disclosed
US-20070071701-A1 Antiperspirant actives and compositions Outdoor Wireless Networks LLC 2007-03-29 US disclosed
EP-0270710-A1 Production of lubricating oil dispersant TEXACO DEVELOPMENT CORPORATION (US) 1988-06-15 EP disclosed
US-4713189-A MANNICH REACTION PRODUCT OF A POLYAMINE, A PHENOL AND AN ALDEHYDE TEXACO, INC. (US) 1987-12-15 US disclosed
US-4713191-A Diiscyanate acid lubricating oil dispersant and viton seal additives TEXACO INC. (US) 1987-12-15 US disclosed
US-4699724-A Post-coupled mono-succinimide lubricating oil dispersant and viton seal additives TEXACO INC. (US) 1987-10-13 US disclosed
US-4663064-A PARTIALLY GLYCOLATED POLYISOBUTYLENE SUCCINIMIDES COUPLED WITH DIACID TEXACO INC. (US) 1987-05-05 US disclosed
US-4636322-A OIL ADDITIVES TEXACO INC. (US) 1987-01-13 US disclosed
EP-0119675-B1 HYDROCARBYL-SUBSTITUTED MONO AND BIS SUCCINIMIDE HAVING POLYAMINE CHAIN LINKED HYDROXYACYL RADICALS AND MINERAL OIL COMPOSITIONS CONTAINING SAME TEXACO DEVELOPMENT CORPORATION (US) 1986-10-29 EP disclosed
US-4482464-A Hydrocarbyl-substituted mono- and bis-succinimide having polyamine chain linked hydroxyacyl radicals and mineral oil compositions containing same TEXACO INC. (US) 1984-11-13 US disclosed
EP-0119675-A1 Hydrocarbyl-substituted mono and bis succinimide having polyamine chain linked hydroxyacyl radicals and mineral oil compositions containing same TEXACO DEVELOPMENT CORPORATION (US) 1984-09-26 EP disclosed