Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.51 |
| ▸ | FYN | P06241 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 10/20 | 0.50 |
| ▸ | CA12 | O43570 | 9/20 | 0.50 |
| ▸ | CA1 | P00915 | 9/20 | 0.50 |
| ▸ | CA9 | Q16790 | 5/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | OGA | O60502 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 5/20 | 0.45 |
| ▸ | CA5A | P35218 | 5/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1921435 | 1.00 | CYP2D6 (0.56) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL9614389 | 1.00 | CYP2D6 (0.56) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL9614375 | 1.00 | CYP2D6 (0.56) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL1357029 | 1.00 | CYP2D6 (0.56) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL3794903 | 1.00 | CYP2D6 (0.56) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL13713745 | 1.00 | CYP2D6 (0.56) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL16946235 | 1.00 | CYP2D6 (0.56) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL3794899 | 1.00 | CYP2D6 (0.56) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL14342159 | 1.00 | CYP2D6 (0.56) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL8908686 | 0.89 | CYP2D6 (0.56) | CYP2D6THRBHSD17B10TSHRNR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312194-B2 | Delivery systems | ALCHEMIA PTY. LTD. (AU) | 2007-12-25 | — | — | US | disclosed |
| US-20040176281-A1 | Delivery systems | ALCHEMIA LIMITED (AU) | 2004-09-09 | — | — | US | disclosed |
| WO-2002053572-A1 | DELIVERY SYSTEMS | ALCHEMIA PTY LTD (AU) | 2002-07-11 | — | — | WO | disclosed |
| WO-1999029705-A2 | SIALYL LEWIS X AND SIALYL LEWIS A GLYCOMIMETICS | GLYCOMED INCORPORATED (US) | 1999-06-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176281-A1 | Delivery systems | MTX2, SGMS2, SGMS1 | CYP2D6 623/4885THRB 4694/4885HSD17B10 1118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.