Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH3A1 | P30838 | 4/20 | 0.45 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.44 |
| ▸ | AR | P10275 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27406411 | 0.80 | CYP3A4 (0.58) | MAPK1CYP3A4TDP1TSHRALDH3A1 | |
| SCHEMBL8055524 | 0.78 | ALDH3A1 (0.49) | MAPK1CYP3A4TDP1TSHRALDH3A1 | |
| SCHEMBL9708914 | 0.77 | MAPK1 (0.51) | MAPK1CYP3A4TDP1TSHRALDH3A1 | |
| SCHEMBL28271263 | 0.75 | CYP3A4 (0.52) | MAPK1CYP3A4TDP1TSHRALDH3A1 | |
| SCHEMBL30182953 | 0.75 | CYP3A4 (0.52) | MAPK1CYP3A4TDP1TSHRALDH3A1 | |
| SCHEMBL10971873 | 0.73 | CYP3A4 (0.57) | MAPK1CYP3A4TDP1TSHRALDH3A1 | |
| SCHEMBL10512417 | 0.72 | MAPK1 (0.68) | MAPK1CYP3A4TDP1TSHRALDH3A1 | |
| SCHEMBL8387943 | 0.72 | ALDH3A1 (0.44) | MAPK1CYP3A4TDP1TSHRALDH3A1 | |
| SCHEMBL414469 | 0.71 | ALDH3A1 (0.51) | MAPK1CYP3A4TDP1TSHRALDH3A1 | |
| SCHEMBL27385554 | 0.70 | CYP3A4 (0.62) | MAPK1CYP3A4TDP1TSHRALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007062198-A1 | METHODS TO ACCELERATE THE ISOLATION OF NOVEL CELL STRAINS FROM PLURIPOTENT STEM CELLS AND CELLS OBTAINED THEREBY | ADVANCED CELL TECHNOLOGY, INC. (US) | 2007-05-31 | — | — | WO | disclosed |
| EP-0422470-A2 | Thiazolcarboxylic acid amide derivatives | BAYER AG (DE) | 1991-04-17 | — | — | EP | disclosed |
| EP-0348736-A1 | Substituted thiadiazolyloxy acetamides | BAYER AG (DE) | 1990-01-03 | — | — | EP | disclosed |
| EP-0224019-A2 | 1-Aryl-4-nitropyrazole | BAYER AG (DE) | 1987-06-03 | — | — | EP | disclosed |