Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27690591 | 0.85 | MAPT (0.48) | ALDH3A1TSHRHCAR3GPR35TDP1 | |
| SCHEMBL11570967 | 0.85 | ALDH3A1 (0.59) | ALDH3A1TSHRHCAR3TDP1MAPK1 | |
| SCHEMBL8811691 | 0.84 | TSHR (0.47) | ALDH3A1TSHRHCAR3GPR35TDP1 | |
| SCHEMBL11576923 | 0.80 | TDP1 (0.59) | ALDH3A1TSHRHCAR3GPR35TDP1 | |
| SCHEMBL3107372 | 0.77 | ALDH3A1 (0.51) | ALDH3A1TSHRHCAR3TDP1MAPK1 | |
| SCHEMBL9708896 | 0.76 | ALDH3A1 (0.50) | ALDH3A1TSHRHCAR3TDP1MAPK1 | |
| SCHEMBL8055524 | 0.75 | ALDH3A1 (0.49) | ALDH3A1TSHRHCAR3TDP1MAPK1 | |
| SCHEMBL9708914 | 0.75 | MAPK1 (0.51) | ALDH3A1TSHRHCAR3TDP1MAPK1 | |
| SCHEMBL9709293 | 0.75 | ALDH3A1 (0.49) | ALDH3A1TSHRHCAR3TDP1MAPK1 | |
| SCHEMBL28056012 | 0.75 | TSHR (0.55) | TSHRGPR35TDP1MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150307889-A1 | HAPLOID MAIZE TRANSFORMATION | CORTEVA AGRISCIENCE LLC | 2015-10-29 | — | — | US | disclosed |
| US-9121032-B2 | Selective ablation of diploid embryos | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-09-01 | — | — | US | disclosed |
| US-8859846-B2 | Doubling of chromosomes in haploid embryos | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2014-10-14 | — | — | US | disclosed |
| US-20130205438-A1 | DOUBLING OF CHROMOSOMES IN HAPLOID EMBRYOS | PIONEER HI BRED INTERNATIONAL INC (US) | 2013-08-08 | — | — | US | disclosed |
| US-20120311736-A1 | SELECTIVE ABLATION OF DIPLOID EMBRYOS | E.I. du Pont de Nemours and Company and Pioneer Hi-Bred International | 2012-12-06 | — | — | US | disclosed |
| US-8269061-B2 | Selective ablation of diploid embryos | E.I. du Pont de Nmeours and Company (US) | 2012-09-18 | — | — | US | disclosed |
| US-20120023612-A1 | SELECTIVE ABLATION OF DIPLOID EMBRYOS | E. I. DU PONT DE NEMOURS AND COMPANY AND PIONEER HI-BRED INTERNATIONAL, INC. (US) | 2012-01-26 | — | — | US | disclosed |
| US-20080216191-A1 | Pollinating silks of maize ear, contacting haploid embryo with chromosome doubling agent (colchicine), propagate cells; generating homozygosity in plants | PIONEER HI-BRED INTERNATIONAL, INC. (US) | 2008-09-04 | — | — | US | disclosed |
| US-20080189801-A1 | Selective Ablation of Diploid Embryos | PIONNER HI-BRED INTERNATIONAL, INC. | 2008-08-07 | — | — | US | disclosed |