Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.44 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10154338 | 0.82 | LMNA (0.52) | LMNAKMT2AALDH1A1MEN1TAAR1 | |
| SCHEMBL16914832 | 0.82 | CA1 (0.55) | LMNAKMT2AALDH1A1MEN1TAAR1 | |
| SCHEMBL23555173 | 0.79 | KMT2A (0.56) | LMNAKMT2AALDH1A1MEN1PARP14 | |
| SCHEMBL30409980 | 0.79 | LMNA (0.52) | LMNAKMT2AALDH1A1MEN1TAAR1 | |
| SCHEMBL51098 | 0.79 | LMNA (0.52) | LMNAKMT2AALDH1A1MEN1TAAR1 | |
| SCHEMBL777513 | 0.79 | ALDH1A1 (0.65) | LMNAKMT2AALDH1A1MEN1TAAR1 | |
| SCHEMBL29468654 | 0.79 | ALDH1A1 (0.65) | LMNAKMT2AALDH1A1MEN1TAAR1 | |
| Hydrochloric Acid SCHEMBL20502511 | 0.78 | LMNA (0.50) | LMNAKMT2AALDH1A1MEN1TAAR1 | |
| SCHEMBL514861 | 0.75 | LMNA (0.52) | LMNAKMT2AALDH1A1MEN1TAAR1 | |
| SCHEMBL785189 | 0.75 | LMNA (0.52) | LMNAKMT2AALDH1A1MEN1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1845083-A2 | New arylsulfonohydrazide inhibitors of enzymes MurC and MurD | UNIVERZA V LJUBLJANI, FAKULTETA ZA FARMACIJO (SI) | 2007-10-17 | — | — | EP | disclosed |