Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA7 | P43166 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4779554 | 0.81 | NUDT1 (0.55) | NUDT1TSHRALDH1A1RAB9AMAPT | |
| SCHEMBL5780556 | 0.81 | KDM4E (0.50) | TSHRALDH1A1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL31633613 | 0.81 | KDM4E (0.50) | TSHRALDH1A1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL28974250 | 0.80 | NUDT1 (0.54) | NUDT1TSHRALDH1A1KDM4EGAA | |
| SCHEMBL14351781 | 0.79 | HTT (0.50) | NUDT1TSHRALDH1A1RAB9AMAPT | |
| SCHEMBL14661485 | 0.79 | NUDT1 (0.52) | NUDT1TSHRALDH1A1MAPTKDM4E | |
| SCHEMBL31214404 | 0.79 | HTT (0.50) | NUDT1TSHRALDH1A1RAB9AMAPT | |
| SCHEMBL17295833 | 0.79 | NUDT1 (0.52) | NUDT1TSHRALDH1A1RAB9AMAPT | |
| SCHEMBL10466297 | 0.79 | NUDT1 (0.52) | NUDT1TSHRALDH1A1RAB9AMAPT | |
| SCHEMBL306569 | 0.78 | CA12 (0.50) | NUDT1TSHRALDH1A1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |