Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28974250 | 0.84 | NUDT1 (0.54) | NUDT1TSHRALDH1A1HSD17B10CA12 | |
| SCHEMBL12633740 | 0.83 | NUDT1 (0.56) | NUDT1TSHRALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL14661485 | 0.83 | NUDT1 (0.52) | NUDT1TSHRALDH1A1HSD17B10CA12 | |
| SCHEMBL17295833 | 0.83 | NUDT1 (0.52) | NUDT1TSHRALDH1A1HSD17B10CA12 | |
| SCHEMBL231051 | 0.83 | NUDT1 (0.52) | NUDT1TSHRALDH1A1HSD17B10CA12 | |
| SCHEMBL13041779 | 0.81 | KDM4E (0.47) | TSHRALDH1A1HSD17B10KDM4ERAB9A | |
| SCHEMBL23674700 | 0.81 | NUDT1 (0.51) | NUDT1TSHRALDH1A1HSD17B10CA12 | |
| SCHEMBL5489653 | 0.81 | NUDT1 (0.51) | NUDT1TSHRALDH1A1HSD17B10CA12 | |
| SCHEMBL109206 | 0.79 | TSHR (0.63) | TSHRALDH1A1HSD17B10CYP1A2HTT | |
| SCHEMBL29571304 | 0.79 | TSHR (0.63) | TSHRALDH1A1HSD17B10CYP1A2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008016811-A2 | AMINOPIPERIDINES AND REALTED COMPOUNDS | NEUROGEN CORPORATION (US) | 2008-02-07 | — | — | WO | disclosed |
| WO-2008016811-A2 | AMINOPIPERIDINES AND REALTED COMPOUNDS | NEUROGEN CORPORATION (US) | 2008-02-07 | — | — | WO | disclosed |
| US-20050239791-A1 | Substituted 1-heteroaryl-4-substituted piperazine and piperidine analogues | NEUROGEN CORPORATION | 2005-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239791-A1 | Substituted 1-heteroaryl-4-substituted piperazine and piperidine analogues | MCHR1, MCHR2, PRLHR | NUDT1 3906/4885TSHR 159/4885ALDH1A1 802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.