SCHEMBL5490010

SCHEMBL5490010

OC(F)=C(F)C(F)(F)C(F)(F)OC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10383614 0.83 THRB (0.30) THRB
SCHEMBL6857739 0.82
SCHEMBL7262110 0.77 THRB (0.60) THRB
SCHEMBL2894825 0.77 THRB (0.60) THRB
SCHEMBL5180100 0.77 THRB (0.43) THRB
SCHEMBL15792486 0.77 THRB (0.60) THRB
SCHEMBL11509926 0.76 LMNA (0.42) THRB
SCHEMBL3313899 0.76 LMNA (0.42) THRB
SCHEMBL3629816 0.76 LMNA (0.42) THRB
SCHEMBL11511027 0.76 LMNA (0.42) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1856530-A2 FLUOROUS-BASED MICROARRAYS Iowa State University Research Foundation, Inc. (US) 2007-11-21 EP disclosed
WO-2006094194-A2 FLUOROUS-BASED MICROARRAYS IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2006-09-08 WO disclosed
US-20060199211-A1 Fluorous-based microarrays IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2006-09-07 US disclosed