Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.51 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.51 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.51 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.51 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.51 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.51 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.51 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ARG1 | P05089 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5489971 | 0.98 | MEN1 (0.53) | MEN1KMT2ACYP1A2ALOX15CYP2C19 | |
| SCHEMBL5058324 | 0.84 | MEN1 (0.70) | MEN1KMT2ACYP1A2ALOX15CYP2C19 | |
| SCHEMBL9601914 | 0.84 | MEN1 (0.70) | MEN1KMT2ACYP1A2ALOX15CYP2C19 | |
| SCHEMBL5058500 | 0.84 | MEN1 (0.70) | MEN1KMT2ACYP1A2ALOX15CYP2C19 | |
| SCHEMBL5058328 | 0.84 | MEN1 (0.70) | MEN1KMT2ACYP1A2ALOX15CYP2C19 | |
| SCHEMBL5664666 | 0.81 | MEN1 (0.49) | MEN1KMT2ACYP1A2ALOX15CYP2C19 | |
| SCHEMBL7809380 | 0.81 | MEN1 (0.49) | MEN1KMT2ACYP1A2ALOX15CYP2C19 | |
| SCHEMBL5489973 | 0.81 | MEN1 (0.49) | MEN1KMT2ACYP1A2ALOX15CYP2C19 | |
| SCHEMBL14521431 | 0.79 | ARG1 (0.51) | MEN1KMT2ACYP1A2ALOX15CYP2C19 | |
| SCHEMBL7745154 | 0.75 | ARG1 (0.44) | MEN1KMT2ACYP1A2ALOX15CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070078082-A1 | Methods and compositions to treat glycosaminoglycan-associated molecular interactions | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2007-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070078082-A1 | Methods and compositions to treat glycosaminoglycan-associated molecular interactions | HPSE, CD44, CSGALNACT1 | MEN1 3711/4885KMT2A 4400/4885CYP1A2 4547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.